The cell technologies in modification of mesh materials used in  urology

Maiborodin, I. V.; Yarin, G Yu; Vilgelmi, I A; Marchukov, S V; Maiborodina, I; Onoprienko, N V

doi:10.18565/urology.2021.2.94-99

Cited by 1 publication

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“…The scientific literature of recent years contains a large amount of data devoted to the study of mesh structures and the possibilities of their modification using MSCs for implantation into patients for correcting tissue defects and pelvic organ prolapse. Based on the literary analysis, Maiborodin et al [ 17 ] studied the influence of cellular technologies on the results of implantation of mesh materials used in urology. The authors conclude that the ideal implant has not yet been created.…”

Section: Cellular Technologies In the Treatment Of Patients With Urin...mentioning

confidence: 99%

Cell Technologies in the Stress Urinary Incontinence Correction

et al. 2022

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The scientific literature of recent years contains a lot of data about using multipotent stromal cells (MSCs) for urinary incontinence correction. Despite this, the ideal treatment method for urinary incontinence has not yet been created. The cell therapy results in patients and experimental animals with incontinence have shown promising results, but the procedures require further optimization, and more research is needed to focus on the clinical phase. The MSC use appears to be a feasible, safe, and effective method of treatment for patients with urinary incontinence. However, the best mode for application of cell technology is still under study. Most clinical investigations have been performed on only a few patients and during rather short follow-up periods, which, together with an incomplete knowledge of the mechanisms of MSC action, does not make it possible for their widespread implementation. The technical details regarding the MSC application remain to be identified in more rigorous preclinical and clinical trials.

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Section: Cellular Technologies In the Treatment Of Patients With Urin...mentioning

confidence: 99%