The causality between gut microbiota and ankylosing spondylitis: Insights from a bidirectional two‐sample Mendelian randomization analysis
Danyan Wang,
Rongqun Li,
Yue Jin
et al.
Abstract:BackgroundThe association between gut microbiota and ankylosing spondylitis (AS) has been reported in the literature; however, whether the two are correlative is unclear.MethodsSingle nucleotide polymorphisms associated with the gut microbiome composition and AS (968 AS cases and 336 191 controls) were obtained from published genome‐wide association studies in this two‐sample Mendelian randomization (MR) study. The causal relationship between gut microbiota and AS was estimated using the inverse‐variance weigh… Show more
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