The causal relationship between depression and frozen shoulder: A two-sample Mendelian randomization
Guang-hua Deng,
Yong-kang Wei
Abstract:To investigate the causal relationship between depression and frozen shoulder using a Mendelian randomization (MR) approach. Pooled data from a large-scale genome-wide association study were used. Genetic loci that were independent of each other and associated with depression and frozen shoulder in populations of European ancestry were selected as instrumental variables. Inverse variance weighting was used as the primary analysis method. Weighted median and MR-Egger were used as complementary analysis methods … Show more
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