The Catecholamine, Cortisol, and Hemodynamic Responses to Mild Perioperative Hypothermia

Frank, Steven M.; Higgins, Michael S.; Breslow, Michael J.; Fleisher, L. A.; Gorman, Robert B.; Stczmann, J. V.; Raff, Hershel; Beattte, C.

doi:10.1097/00132586-199512000-00041

Cited by 35 publications

(52 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Cooling results in increased gluconeogenesis and glycogenolysis, which may be due to a rise in circulating catecholamines. [38][39][40] Hyperglycemia after anoxic brain injury has been associated with poor outcomes. 41 In addition, tight glycemic control in both medical and surgical patients in intensive care units improves outcomes.…”

Section: Endocrine and Metabolicmentioning

confidence: 99%

“…25,45 Initially, hypothermia is associated with an increase in heart rate that may be related to adrenergic stimulation. [38][39][40] The heart rate is ultimately slowed during mild hypothermia; this is likely a result of the direct effect of hypothermia on the pacemaker rate. 33,34 As a general rule, mild bradycardia can be expected and is generally well tolerated, as shown in clinical trials of therapeutic hypothermia after sudden cardiac arrest.…”

Section: Cardiovascularmentioning

confidence: 99%

“…Agents such as epinephrine and dopamine may be administered to increase heart rate and blood pressure. 5,34,39 If the patient remains unstable, passive rewarming should be abandoned in favor of active rewarming.…”

Section: Cardiovascularmentioning

confidence: 99%

“…53,54 Hypothermia also decreases the fibrillation threshold and increases adrenergic stimulation secondary to catecholamine release. [38][39][40]53 It is unclear whether advanced cardiac life support algorithms applied during normothermia are useful during therapeutic hypothermia. [55][56][57][58] Electrical defibrillation for ventricular fibrillation is reportedly ineffective at core temperatures below 30°C, and it may be less effective at a core temperature of 32°C versus 37°C.…”

Section: Cardiovascularmentioning

confidence: 99%

See 3 more Smart Citations

Practical Pharmacologic Aspects of Therapeutic Hypothermia After Cardiac Arrest

Arpino¹,

Greer

2008

Pharmacotherapy

View full text Add to dashboard Cite

Therapeutic hypothermia has emerged as an effective means of improving neurologic outcomes among cardiac arrest survivors. To achieve optimal results, clinicians must understand and anticipate potential adverse effects of cooling and provide rigorous monitoring and/or pharmacologic interventions as appropriate. Using pharmacotherapy to counter adverse effects of cooling or to treat an intrinsic process under hypothermic conditions requires understanding how hypothermia will influence the clinical effects of the drug, including the drug's pharmacokinetics and pharmacodynamics. The pharmacologic aspects of therapeutic hypothermia in relation to physiology and adverse effects are reviewed.

show abstract

Section: Endocrine and Metabolicmentioning

confidence: 99%

Section: Cardiovascularmentioning

confidence: 99%

Section: Cardiovascularmentioning

confidence: 99%

Section: Cardiovascularmentioning

confidence: 99%

See 2 more Smart Citations

Practical Pharmacologic Aspects of Therapeutic Hypothermia After Cardiac Arrest

Arpino¹,

Greer

2008

Pharmacotherapy

View full text Add to dashboard Cite

show abstract

“…To reduce radiant heat loss, multiple insulating layers were placed over the pigs. Mild core hypothermia has been associated with an increase in circulating catecholamine concentrations leading to tachycardia, systemic vascular constriction and hypertension (Frank et al 1995). Therefore hypothermia may have been a contributory factor to the tachycardic responses seen during CED.…”

Section: Discussionmentioning

confidence: 99%

Anaesthetic complications in pigs undergoing MRI guided convection enhanced drug delivery to the brain: a case series

Jones

Bienemann

Barua

et al. 2012

Veterinary Anaesthesia and Analgesia

View full text Add to dashboard Cite

Cytoreductive Surgery With Hyperthermic Intraperitoneal Chemotherapy, Part II: Implementation

Dunn¹,

Ciccarelli²,

Moltzen³

2019

AORN Journal

View full text Add to dashboard Cite

Cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) is an extensive procedure used to treat peritoneal carcinomatosis, which is either primary or secondary to other cancers (eg, ovarian, colorectal, appendiceal) that have metastasized to the peritoneum. Morbidity, mortality, and quality of life have improved for patients selecting CRS with HIPEC as a cancer treatment. At Holy Name Medical Center in Teaneck, New Jersey, an interdisciplinary team was established to plan and coordinate performing this new procedure in the OR. The team created a written protocol for implementing CRS with HIPEC before patients were scheduled for surgery. This article explores the perioperative facets of implementing CRS with HIPEC and discusses care of the patient undergoing CRS with HIPEC, with a focus on perioperative nursing considerations.

show abstract

The Catecholamine, Cortisol, and Hemodynamic Responses to Mild Perioperative Hypothermia

Cited by 35 publications

References 0 publications

Practical Pharmacologic Aspects of Therapeutic Hypothermia After Cardiac Arrest

Practical Pharmacologic Aspects of Therapeutic Hypothermia After Cardiac Arrest

Anaesthetic complications in pigs undergoing MRI guided convection enhanced drug delivery to the brain: a case series

Cytoreductive Surgery With Hyperthermic Intraperitoneal Chemotherapy, Part II: Implementation

Contact Info

Product

Resources

About