The case of granuloma annulare associated with
            <scp>SARS‐CoV</scp>
            ‐2 infection

Emre, Selma; Unal, Esranur; Çelik, Burak; Süngü, Nuran

doi:10.1111/dth.15369

Cited by 5 publications

(8 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Granuloma annulare (GA) is a non-infectious granulomatous skin reaction with potential triggers that can affect adult and pediatric populations. The etiology of GA is unknown, but medication, infection, trauma, insect bites, and vaccination have been reported as triggering factors [1][2][3]. Solitary, erythematous, annular papules, and plaques are found predominantly in the acral regions.…”

Section: Introductionmentioning

confidence: 99%

Clinical and Histopathological Evaluation of Forty-one Cases of Pediatric Granuloma Annulare

Aksu¹,

Erdil²,

Baş³

et al. 2023

Dermatol Pract Concept

View full text Add to dashboard Cite

Introduction: Granuloma annulare (GA) is a non-infectious granulomatous disease that can affect children and adults. Although many studies have been conducted adult GA patients, the literature on pediatric GA cases is limited. Objectives: Therefore, this study aimed to examine the demographic, clinical, and pathological features of pediatric GA cases. Methods: This study was performed retrospectively in a single-center tertiary dermatology hospital. Demographic characteristics and clinical and histopathological features were recorded. Results: Forty-one participants were included in this study, of which 66% were female. The mean age was 3.8 ± 2.6 years, and the mean lesion duration was 7.5 ± 10.3 months. The involvement of 78% of the patients was localized, and the remaining 22% was generalized. Asthma (30%) was the most common comorbid disease. Histopathological examination was performed on twenty-one patients, and the infiltrate pattern was interstitial in 71% of the cases and palisadic in 29%. Generalized distribution, trunk involvement, and concomitant disease tended to be higher in patients with an interstitial pattern than in those with a palisadic pattern. Conclusions: Atopy and asthma should be questioned in pediatric GA cases. There are differences between involvement, distribution, concomitant disease, and histopathological patterns, which may indicate differences in pathogenesis.

show abstract

Section: Introductionmentioning

confidence: 99%

Clinical and Histopathological Evaluation of Forty-one Cases of Pediatric Granuloma Annulare

Aksu¹,

Erdil²,

Baş³

et al. 2023

Dermatol Pract Concept

View full text Add to dashboard Cite

show abstract

“…The second patient was a 31 years-old woman with an annular, irregular, pink-coloured erythematous 3×2 in diameter papular lesion on the dorsum of the left foot, arising ten days after an RT-PCR SARS-CoV-2 positive test. Histology revealed an interstitial GA [7] .…”

Section: Discussionmentioning

confidence: 96%

“…GA arising both after SARS-CoV-2 infection and vaccination are exceptional and unexpected events: three cases of GA after SARS-CoV-2 infection and one after SARS-CoV-2 vaccination have been reported in the literature ( Table 1 ) [2] , [5] , [6] , [7] , [8] .…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Granuloma annulare after SARS-CoV-2 vaccination: A case report and a literature review

Russo

Accarino

Varricchio

et al. 2023

Pathology - Research and Practice

View full text Add to dashboard Cite

“…Despite its uncertain etiology, it has been associated with diabetes mellitus type I, dyslipidemia, trauma, thyroid gland disease, malignancy, viral infections, medications, vaccinations and the HLA-B35 haplotype [2]. Until now, only a few cases triggered by SARS-CoV-2 virus have been reported, in particular localized, generalized and subcutaneous forms [1][2][3][4][6][7][8][9]. Herein we present a case of diffuse patch GA in a female patient, occurring one month after infection with SARS-CoV-2.…”

Section: Introductionmentioning

confidence: 99%

Post COVID - 19 Infection Diffuse Patch Granuloma Annulare in a Female Patient with Rheumatoid Arthritis: A Case Report

Gravani

2023

JDR

View full text Add to dashboard Cite

Introduction: Granuloma Annulare (GA) is a benign, usually self-limited, inflammatory granulomatous skin disorder of unknown etiology and with a diversity of clinical variants. Genetic factors, associations with predisposing diseases along with several triggers such as certain infections and vaccines, have been described, SARS-CoV-2 virus being one of them. Case Presentation: Localized, generalized and subcutaneous forms of GA have been reported following either SARS-CoV-2 infection or vaccination against the virus. Herein we present a case of diffuse patch GA in a middle-aged female patient with medical history of rheumatoid arthritis, one month after catching COVID -19 despite being fully vaccinated against the virus. Discussion: Overall, taking into account the relevant literature, the occurrence of GA after infection with SARS-CoV-2 as well as after vaccination seems to be attributed to the activation of an immunologic reaction rather than to the direct effect of the virus on the skin lesions, with the latest also appearing in the form of diffuse patch rashes. Conclusion: Dermatologists should be aware of such lesions appearing after COVID-19 infection or even vaccination especially in patients with autoimmune diseases.

show abstract

The case of granuloma annulare associated with SARS‐CoV ‐2 infection

Cited by 5 publications

References 5 publications

Clinical and Histopathological Evaluation of Forty-one Cases of Pediatric Granuloma Annulare

Clinical and Histopathological Evaluation of Forty-one Cases of Pediatric Granuloma Annulare

Granuloma annulare after SARS-CoV-2 vaccination: A case report and a literature review

Post COVID - 19 Infection Diffuse Patch Granuloma Annulare in a Female Patient with Rheumatoid Arthritis: A Case Report

Contact Info

Product

Resources

About