The cardiovascular manifestations of influenza: A systematic review

Raisi‐Estabragh, Zahra; Mamas, Mamas A.

doi:10.1016/j.ijcard.2013.01.274

Cited by 150 publications

(139 citation statements)

References 68 publications

Supporting

Mentioning

123

Contrasting

Unclassified

Order By: Relevance

“…However, case reports indicate similar presentations as other strains of influenza A (2). Here, we present a case of H1N1 infection leading to pericarditis and subsequent pericardial effusion with cardiac tamponade.…”

Section: Introductionmentioning

confidence: 55%

Influenza H1N1 infection leading to cardiac tamponade in a previously healthy patient: A case report

Bainey¹,

Sidhu²,

Sharma³

et al. 2016

Res Cardiovasc Med

View full text Add to dashboard Cite

Introduction: The cardiac manifestations of influenza A are broad, ranging from self-limited pericarditis to fatal cardiomyopathy. The 2009 H1N1 influenza A (H1N1) strain is a rare cause of pericarditis, and its role in developing a pericardial effusion leading to tamponade has infrequently been reported. Case Presentation: We describe a case of a young female with no prior cardiovascular history who presents with a pericardial effusion and shock secondary to cardiac tamponade from pericarditis due to H1N1 influenza A. Conclusions: This case highlights the potential severity of H1N1 infections and the utility of considering cardiac tamponade in patients presenting with influenza symptoms and circulatory collapse.

show abstract

Section: Introductionmentioning

confidence: 55%

Influenza H1N1 infection leading to cardiac tamponade in a previously healthy patient: A case report

Bainey¹,

Sidhu²,

Sharma³

et al. 2016

Res Cardiovasc Med

View full text Add to dashboard Cite

show abstract

“…Influenza is a recognized cause of myocarditis, which can lead to significant impairment of cardiac function and mortality [2,3,6]. Myocarditis is not the major cause of death from influenza infection, and is very rare.…”

Section: Citationmentioning

confidence: 99%

“…Pan et al investigated the molecular mechanism of influenza virus-associated myocarditis and revealed the importance of trypsin induction and the increased production of matrix metalloproteinase and proinflammatory cytokines in the pathogenesis of acute myocarditis [32,35]. Along with the direct effect of influenza virus infection, proinflammatory cytokines and endothelial cell dysfunction are thought to contribute to the pathogenesis of severe clinical features, including severe cardiac dysfunction, in patients infected with influenza virus [2,3,6,32,35].It was reported that osertamivir has pleotropic effects [30,[36][37][38]. In human, compared with the partial reduction of viral shedding, proinflammatory cytokines are completely suppressed by oseltamivir use [36].…”

Section: Citationmentioning

confidence: 99%

See 1 more Smart Citation

The Neuraminidase Inhibitor Peramivir Ameliorates Myocarditis Induced by Influenza A (H1n1pdm) Virus in a Murine Model

Ukimura¹,

Ooi²,

Kanzaki

2015

Clin Microbiol

View full text Add to dashboard Cite

Severe influenza sometimes causes myocarditis. To analyze the effects of peramivir on influenza A (H1N1pdm) virus myocarditis, we investigated survival rates, cardiac function, histological findings and cytokine induction in murine influenza A (H1N1pdm) virus-induced myocarditis. Eight-week-old BALB/c male mice were infected intranasally with influenza A (H1N1pdm) virus, and then divided into 2 groups: control group, which was injected with saline; and peramivir-treatment group, which was treated with peramivir. Histological studies, echocardiograms and quantitative analysis of viral RNA and mRNA for inflammatory cytokines and adhesion molecules were performed. Treatment with peramivir led to a significant improvement in survival (p<0.01 vs. control group). Fractional shortening (FS) of peramivir-treatment group (44.7%, p<0.01) was significantly higher than that of control group (27.7%) on day 8. Histological examinations revealed localized myocarditis with lymphocyte infiltration, and myocarditis lesions were found in perivascular areas or associated with pericarditis; treatment with peramivir improved these findings. Quantity of influenza virus genome in heart and lung tissues was suppressed in peramivirtreatment group. The expression of cytokine and adhesion molecule mRNA was suppressed in peramivir-treatment group. Peramivir improved influenza A (H1N1pdm) virus-induced myocarditis.

show abstract

“…3 Although difficult to diagnose, right atrial thrombus is a complication with deadly consequences, like pulmonary embolus and right heart obstruction, that must be prevented by proper approach and management of the catheter, early clinical suspicion, diagnosis and appropriate intervention. 1 Authors describe management of a 64-yearold man with hemodialysis catheter induced right atrial thrombus, conditioning cardiac arrest and a review of the existing literature.…”

Section: Bibliografía Introductionmentioning

confidence: 99%