The cardiotoxic effects of CAR‐T cell therapy: An updated systematic review and meta‐analysis
Roberto A. S. V. Mazetto,
Sarah O. N. Monteiro,
Elísio Bulhões
et al.
Abstract:BackgroundChimeric antigen receptor T‐cell (CAR‐T) therapy has shown promise in treating hematologic malignancies, yet its potential cardiotoxic effects require thorough investigation.ObjectivesWe aim to conduct a systematic review and meta‐analysis to examine the cardiotoxic effects of CAR‐T therapy in adults with hematologic malignancies.MethodsWe searched PubMed, Embase, and the Cochrane Central Register of Controlled Trials for studies reporting cardiovascular outcomes, such as arrhythmias, heart failure, … Show more
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