The Cardiopulmonary Effects of Calcitonin-Gene Related Peptide Family

Abstract

The cardiopulmonary diseases are very common in the population. They are high-cost diseases and there are still no definitive treatments. The roles of members of the calcitonin-gene-related peptide (CGRP) family in the cardiopulmonary diseases have been studied for many years and promising results are obtained. Especially in recent years, two important members of the family, adrenomedullin and adrenomedullin2/intermedin, are considered as new treatment targets in cardiopulmonary diseases. In this review, the roles of CGRP family peptides in cardiopulmonary diseases has been investigated according to the studies that were performed to the present day.