INTRODUCTIONDeath is an inevitable end of life. For perpetuation of species, reproduction is thus essential. Reproductive life in women is more protracted and dynamic than in men. Pregnancy constitutes an additional alteration in the women's reproductive life. During the course of pregnancy, the fetus gradually grows and therefore, brings about generalized systemic changes in the mother to accommodate and adapt to the needs of developing fetus. Anatomical, physiological and biochemical adaptations that occur during pregnancy and profound changes in respiratory physiology are a part of the same process.1 Pregnancy represents one of the best examples of selective adaptation in terms of respiratory physiology.Static pulmonary function tests permit an accurate and reproducible assessment of the functional state of the respiratory system and allow quantification of the severity of disease. Its precise knowledge allows the clinician to verify the extent of the adaptation in pregnant women and helps to avoid unnecessary treatment of physiological changes misinterpreted as pathological in reference to pre-pregnancy standards.2 This knowledge of the expected or desired changes in pulmonary parameters is fundamental to understanding of how the disease states affect pregnancy and vice versa.3 Understanding of the maternal pulmonary function adjustments helps to avoid inappropriate diagnosis and unnecessary intervention. Information regarding status of pulmonary function is also essential for assessment of fitness for anaesthesia. 4 Various investigators have studied pulmonary function tests during normal pregnancy but their results were conflicting. [5][6][7][8][9] Although there are reports of changes in pulmonary function tests during pregnancy, not much work has been done specifically in third trimester. The above observations gave us an impetus to study the ABSTRACT Background: Pregnancy represents one of the best examples of selective adaptation in terms of respiratory physiology. Objective of the study is to evaluate the changes in static pulmonary function tests (PFTs) in third trimesters of pregnancy (study group) and compare with non-pregnant women (control group). Methods: 65 subjects (study group 35 subjects and control group 30 subjects) from a tertiary care hospital of Mumbai were included in the study. Pulmonary function tests (PFTs) was done by computerized spirometry. Results: Statistical analysis was carried out and paired t-test was applied. Significant increase in mean inspiratory capacity and significant decrease in mean expiratory reserve volume were observed in the third trimester of normal pregnant women as compared to normal non-pregnant women.
Conclusions:The present study highlights observation that there is no respiratory impairment due to pregnancy, as adaptive changes in respiratory system compensate for the altered structure and function of the maternal body and very well suffice for the increased needs of pregnancy.