The Carbohydrate Metabolism of the Marantic Infant

Calorie requirements for growth after severe undernutrition.

“…Montgomery (1962), moreover, by showing that the resting metabolic rates rose during recovery to figures well above the accepted normals for children of the same weight, appeared at the time to have confirmed this and to have overruled the findings of the few clinicians who had found that older 'marasmic' children gained weight as well as or better than normal children if they were given enough food (Tisdall, Drake, and Brown, 1925;Wang et al, 1926). Montgomery's findings, moreover, ran counter to the work on animals, for Thompson and Mendel (1918), Jackson (1937), and Mendes and Waterlow (1958) had found that malnourished rats responded normally to an increase in the necessary foodstuffs, and McCance (1960) and Mount et al (1963) that cockerels and pigs behaved in exactly the same way.…”

Glycemia in Cachexia of Nurslings

“…We know that, schematically, the metabolism of saccharin is sub¬ mitted to endocrine antagonistic regulative actions represented by the islands of Langerhans and their incretion insulin, which (1) blocks the beginning formation of dextrose from proteins and fats, (2) in a first period, increases the glycogen synthesis in liver and muscles and causes hypoglycemia by the association of both mechanisms and (3) finally (if the nutritious amount of carbohydrates is not sufficient) impoverishes the liver and muscles in glycogen, as with the extraglycogenic source (fats and proteins) cut off glycogen alone must provide for the organic requirements of dextrose.…”

The Production of a Lowered Carbohydrate Tolerance in Dogs

“…7. This intoxication may produce its effect on the sugar tolerance values either by an increase in the glycogenolytic function of the body or by an impairment of the ability of the organism to store carbohydrate.…”