The cancer incidence temporality index: An index to show temporal changes in the age of onset of overall and specific cancer (England and Wales, 1971–1999)

Newby, J.A.; Busby, Chris; Howard, C. Vyvyan; Platt, Mary-Jane

doi:10.1016/j.biopha.2007.05.002

Cited by 9 publications

(6 citation statements)

References 30 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Only DDE showed significant age correlation in females uncorrected P=0.048. (33,40) found a positive correlation of both p, p' DDT and DDE with age.…”

Section: Discussionmentioning

confidence: 91%

Estimation of Some Carcinogenic Pesticides Overload in Human Adipose Tissue

Hussien

2009

Biochemistry Letters

View full text Add to dashboard Cite

Polychlorinated biphenyls (PCBs) are potentially hazardous compounds in the environmental pollution for human beings persistent. The high lipophilicity and the resistance to biodegradation of PCBs allow the bioaccumulation of these chemicals in the fatty tissues of organisms.To test the hypothesis that the amount and quality of organochlorine residues in adipose tissue related to the tumor incidence, the PCBs body burden in patients was studied. The objective of this study was to determine the levels of PCBs in the adipose tissue of different patients lived in Delta Egypt especially Al-Dakhelia, Al-Garbia, and Damietta which were the most probably used pesticides.

show abstract

“…Only DDE showed significant age correlation in females uncorrected P=0.048. (33,40) found a positive correlation of both p, p' DDT and DDE with age.…”

Section: Discussionmentioning

confidence: 91%

Estimation of Some Carcinogenic Pesticides Overload in Human Adipose Tissue

Hussien

2009

Biochemistry Letters

View full text Add to dashboard Cite

show abstract

“…We have previously analysed the effect of these two factors on prostate cancer incidence, concluding that improvement in screening detection by the routine use of Prostate-Specific Antigens (PSA) test cannot per se fully account for the currently growing incidence of this cancer (18). Similarly, we have pointed out that increase in life expectancy cannot explain why rising prostate cancer incidence affects all age categories (19), why it is more perceptible in young people than in the elderly (20) and why it occurs at an earlier stage in life (21).…”

Section: Discussionmentioning

confidence: 92%

Prostate cancer as an environmental disease: An ecological study in the French Caribbean islands, Martinique and Guadeloupe

Belpomme¹

2009

Int J Oncol

View full text Add to dashboard Cite

Abstract. Using a transdisciplinary methodological approach we have conducted a multifactorial analysis in Martinique and Guadeloupe in order to elucidate the aetiology of prostate cancer. In 2002, world age standardized rates of prostate cancer were 152 new cases per 100,000 person-years in the two islands; one of the highest worldwide rates and much higher than those reported for other Caribbean islands and metropolitan France. Using a linear regression analysis, we found that the growth curves of incidence rates for Martinique and metropolitan France have been significantly diverging since 1983. That these curves are not parallel suggests that although a Caribbean genetic susceptibility factor may be involved in carcinogenesis, this factor cannot per se account for the observed growing incidence. On the basis of mapping analysis of soil pollution, we further showed that water contamination by pesticides originates from banana plantations. Moreover, we have established retrospectively that general population subjects investigated in 1972 in Martinique for the presence of organochlorinated pesticides in their adipose tissue had been contaminated by extremely high levels of DDT, DDE, ·, ß and ÁHCH, aldrin and dieldrin. Our study leads to the conclusion that the growing incidence of prostate cancer cannot be related either to a modification of ethnographic factors nor to a change in lifestyle and therefore suggests that environmental factors such as the intensive and prolonged exposure to carcinogenic, mutagenic and reproductive toxin pesticides may cause prostate cancer.

show abstract

“…Environmental agents have also been identified as a key potential source of carcinogenesis, especially given that more than 85% of cancers do not appear to be attributable to known causal factors (Belpomme ). In the words of Clapp et al (:633): “The scientific literature provides substantial evidence of environmental and occupational causes of cancer and fully justifies accelerated efforts to prevent carcinogenic exposures.” In light of the fact that the key risk factor for cancer is age, others point to an aging population and improvements in diagnostic testing as largely responsible for the increase in cancer seen in the 20th century (e.g., Newby et al ).…”

Section: Cancer and Lifestyle: The Evidence In Contextmentioning

confidence: 99%

“…In the words of Clapp et al (2007:633): "The scientific literature provides substantial evidence of environmental and occupational causes of cancer and fully justifies accelerated efforts to prevent carcinogenic exposures." In light of the fact that the key risk factor for cancer is age, others point to an aging population and improvements in diagnostic testing as largely responsible for the increase in cancer seen in the 20th century (e.g., Newby et al 2007).…”

Section: Cancer and Lifestyle: The Evidence In Contextmentioning

confidence: 99%

Communicating “Evidence”: Lifestyle, Cancer, and the Promise of a Disease‐free Future

Bell

Ristovski-Slijepcevic

2015

Med Anthropol Q

View full text Add to dashboard Cite

In the era of evidence-based health care, conferences aimed at disseminating scientific knowledge perform an essential role in shaping policy and research agendas and transforming physician practice. Drawing on observations at two U.S. cancer prevention conferences aimed at knowledge translation, we examine the ways that evidence regarding the relationship between cancer and lifestyle is articulated and enacted. We show that characterizations of the evidence base at the conferences far outstripped what is presently known about the relationship between cancer and lifestyle. The messages presented to conference participants were also personalized and overtly moralistic, with attendees engaged not merely as practitioners but as members of the public at risk for cancer. We conclude that conferences seeking to bring together knowledge "makers" and knowledge "users" play a potentially important role in the production of scientific facts and are worthy of further study as distinct sites of knowledge production.

show abstract

The cancer incidence temporality index: An index to show temporal changes in the age of onset of overall and specific cancer (England and Wales, 1971–1999)

Cited by 9 publications

References 30 publications

Estimation of Some Carcinogenic Pesticides Overload in Human Adipose Tissue

Estimation of Some Carcinogenic Pesticides Overload in Human Adipose Tissue

Prostate cancer as an environmental disease: An ecological study in the French Caribbean islands, Martinique and Guadeloupe

Communicating “Evidence”: Lifestyle, Cancer, and the Promise of a Disease‐free Future

Contact Info

Product

Resources

About