The burden of severe cases of Influenza disease: the Friuli Venezia Giulia Region experience

The burden of seasonal influenza in Italy: A systematic review of influenza‐related complications, hospitalizations, and mortality

“…Twenty‐four articles were then screened by full text, and eight studies were excluded with the following reasons: did not meet the inclusion criteria ( n = 2), not related to the topic ( n = 4), reviews (=2). Eventually, 16 articles 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 published from 2001 to 2020 were included in the qualitative synthesis. Details about the study selection process are shown in the flowchart (Figure 1 ).…”

“…Seven studies (43.7%) were conducted in the Northern Italy, 22 , 23 , 25 , 27 , 28 , 30 , 33 three (19.7%) in Central Italy, 26 , 31 , 32 and one in Southern Italy. 29 Four (25%) were nationwide studies 24 , 34 , 35 , 36 and one (6.2%) was conducted both in Lombardy (in Northern Italy) and Apulia (in Southern Italy).…”

“…Five studies (31.2%) were set into a hospital, 22 , 25 , 27 , 32 , 33 one (6.2%) in a residential drug‐rehabilitation community, 26 six (37.5%) in a primary care setting, 23 , 28 , 29 , 30 , 31 , 37 and four (25%) were based on administrative health data. 24 , 34 , 35 , 36 Regarding studies set in a primary care setting, one (16.67%) was set into a health care unit, 33 one (16.67%) in the district of a local health authority (LHA), 30 and four (66.67%) based on general practitioners (GPs) or primary care pediatricians (PCPs).…”

“…Three articles (19.7%) concerned the pediatric age, 27 , 28 , 32 three articles (18.7%) concerned adulthood, 22 , 26 , 37 and four (25%) old age, 25 , 30 , 31 , 33 whereas four (25%) articles referred to the entire population without age distinction. 24 , 34 , 35 , 36 …”

“…Eight studies reported data on only one season 22 , 26 , 27 , 28 , 29 , 31 , 33 , 37 ; Rizzo et al reported data from 1970 to 2001, 34 , 35 and Bertolani et al reported data from 2008 to 2015. 24 The other studies reported data on a period of up to four seasons.…”