The burden of pancreatic cancer is rising in Brazil

Lotufo, Paulo A.

doi:10.1590/1516-3180.2019.13752231019

Cited by 1 publication

(2 citation statements)

References 11 publications

(16 reference statements)

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“…The results of this study, using standardized methodology, converge with the findings of studies using other methodologies, which show a tendency for an increase in the burden of pancreatic cancer in Brazil and worldwide [1][2][3]6,[18][19][21][22][23] . Moreover, this study described an evident influence of the level of social development in the magnitude and the annual growth of the rates of incidence and mortality in Brazil, in its states, as well as in the comparator countries.…”

Section: Discussionsupporting

confidence: 80%

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The increasing burden of pancreatic cancer in Brazil from 2000 to 2019: estimates from the Global Burden of Disease Study 2019.

Chaves

Bastos

Almeida

et al. 2022

Rev. Soc. Bras. Med. Trop.

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Introduction: Pancreatic cancer is increasing worldwide. The burden of pancreatic cancer in Brazil and its states was analyzed and compared with that from the USA and China. Methods: This is a descriptive study of the incidence and mortality estimates from the Global Burden of Disease 2019 study, from 2000 to 2019. The Brazilian states presenting the highest and lowest socio-demographic index (SDI) were selected from each of the five regions. The SDI consists of the per capita income, education, and fertility rate of each population. Results: A significant increase was found in age-standardized incidence and mortality of pancreatic cancer in all three countries, with differences in magnitude and annual increases. In Brazil, this incidence rose from 5.33 [95% Uncertainty Interval (UI): 5.06-5.51] to 6.16 (95% UI: 5.68-6.53) per 100,000 inhabitants. China and the Brazilian states with the lowest SDI, such as Pará and Maranhão, showed lower incidence and mortality rates, although presenting the highest annual increases. No difference was found between the sexes. A higher mortality rate was observed for those individuals of 70+ years, which was three to four times higher than those aged 50 to 69 years. Conclusions: The increasing burden of pancreatic cancer in the studied countries, and the higher estimates for the elderly in a fast-aging country such as Brazil, indicates that more resources and health policies will be necessary. The greatest increase in the states with lower SDI reflects inequalities in the access to diagnosis and registries of this cancer.

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Section: Discussionsupporting

confidence: 80%

“…In Brazil, as well as in many countries around the world, mortality rates for pancreatic cancer have been increasing 1 , 2 . It is the most fatal of the main types of cancer, with an average time of survival of only about 6 months, with a 5-year survival rate of approximately 6% 3 , 4 , 5 .…”

Section: Introductionmentioning

confidence: 99%