The Burden of Bereavement: Early-Onset Depression and Impairment in Youths Bereaved by Sudden Parental Death in a 7-Year Prospective Study

Pham, Steven; Porta, Giovanna; Biernesser, Candice; Payne, Monica Walker; Iyengar, Satish; Melhem, Nadine M.; Brent, David A.

doi:10.1176/appi.ajp.2018.17070792

Cited by 84 publications

(57 citation statements)

References 40 publications

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“…Many studies have linked parental death with depression. 7,8 However, our data also confirm the negative effects on adult physical health. 6,[14][15][16][17][18] The study by Neeleman et al (2002) 15 analysed 20 chronic diseases and found a higher risk in adults whose parents had died before they were 16 years old.…”

Section: Early Parental Death and Diseasessupporting

confidence: 77%

Early parental death and psychosocial risk factors for dementia: A case–control study in Europe

Conde-Sala

Garré-Olmo

2020

Int J Geriat Psychiatry

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Objectives To assess the association between early parental death and the risk of dementia in adult life and to examine the risk factors associated with early parental death in people with and without dementia. Methods/design A population‐based case–control study of a sample of 65 997 participants from the Survey of Health, Ageing and Retirement in Europe study. Early parental death was operationalized as parental death at the age of ≤16 years. Main analyses were conducted using bivariate and multivariate logistic regression analyses. Results The odds ratio (OR) for dementia in individuals who experienced early parental death (father or mother) at the age of ≤16 years was 1.83 (95%CI 1.61‐2.09) and 1.54 (95%CI 1.35‐1.76) adjusted for age, gender and education. In the multivariate logistic regression analysis carried out with the whole sample, early parental death increased the risk of dementia (OR = 1.50, 95%CI 1.31‐1.72), along with older age (OR = 5.92, 95%CI 4.86‐7.17), neuroticism (OR = 2.94, 95%CI 2.61‐3.31), low education level (OR = 1.84, 95%CI 1.64‐2.05) and low income (OR = 1.49, 95%CI 1.34‐1.67). Discussion Early parental death (≤16 years) was associated with an increased risk of dementia. We discuss the neurobiological markers associated with adverse childhood experiences (ACEs) and dementia as well as interventions to counteract the negative health effects on adults. J Am Geriatr Soc 68:‐, 2020.

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Section: Early Parental Death and Diseasessupporting

confidence: 77%

Early parental death and psychosocial risk factors for dementia: A case–control study in Europe

Conde-Sala

Garré-Olmo

2020

Int J Geriat Psychiatry

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“…Depression after bereavement is common, with longitudinal assessments indicating that 20–25% of bereaved people develop depression at some point (Galatzer-Levy and Bonanno, 2012; Maccallum et al, 2015; Pham et al, 2018). Prior to DSM-5, clinicians were advised to use caution in diagnosing depression after bereavement because it may result in over-diagnosis in the context of expected levels of grief.…”

Section: Classificationmentioning

confidence: 99%

The 2020 Royal Australian and New Zealand College of Psychiatrists clinical practice guidelines for mood disorders

Malhi

Bell

Bassett³

et al. 2020

Aust N Z J Psychiatry

322

365

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Objectives: To provide advice and guidance regarding the management of mood disorders, derived from scientific evidence and supplemented by expert clinical consensus to formulate s that maximise clinical utility. Methods: Articles and information sourced from search engines including PubMed, EMBASE, MEDLINE, PsycINFO and Google Scholar were supplemented by literature known to the mood disorders committee (e.g. books, book chapters and government reports) and from published depression and bipolar disorder guidelines. Relevant information was appraised and discussed in detail by members of the mood disorders committee, with a view to formulating and developing consensus-based recommendations and clinical guidance. The guidelines were subjected to rigorous consultation and external review involving: expert and clinical advisors, key stakeholders, professional bodies and specialist groups with interest in mood disorders. Results: The Royal Australian and New Zealand College of Psychiatrists mood disorders clinical practice guidelines 2020 (MDcpg2020) provide up-to-date guidance regarding the management of mood disorders that is informed by evidence and clinical experience. The guideline is intended for clinical use by psychiatrists, psychologists, primary care physicians and others with an interest in mental health care. Conclusion: The MDcpg2020 builds on the previous 2015 guidelines and maintains its joint focus on both depressive and bipolar disorders. It provides up-to-date recommendations and guidance within an evidence-based framework, supplemented by expert clinical consensus. Mood disorders committee: Gin S Malhi (Chair), Erica Bell, Darryl Bassett, Philip Boyce, Richard Bryant, Philip Hazell, Malcolm Hopwood, Bill Lyndon, Roger Mulder, Richard Porter, Ajeet B Singh and Greg Murray.

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“…At the same time studies (e.g. Nielsen et al, 2012;Pham et al, 2018) indicate that nearly half of all bereaved children have experienced daily impairments to their daily functioning. Therefore, schools should make it a high priority to offer bereaved children support throughout the difficult experience of loss.…”

Section: Introductionmentioning

confidence: 98%

Loss in the family – A reflection on how schools can support their students

Dyregrov

Lytje

2020

Bereavement Care

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The Burden of Bereavement: Early-Onset Depression and Impairment in Youths Bereaved by Sudden Parental Death in a 7-Year Prospective Study

Abstract: Parental death increased the incidence of depression in offspring early in the course of bereavement. Early identification and treatment of depression in bereaved youths and augmentation of family resilience may protect against later sequelae of functional impairment.

Cited by 84 publications

References 40 publications

Early parental death and psychosocial risk factors for dementia: A case–control study in Europe

Early parental death and psychosocial risk factors for dementia: A case–control study in Europe

The 2020 Royal Australian and New Zealand College of Psychiatrists clinical practice guidelines for mood disorders

Loss in the family – A reflection on how schools can support their students

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