The brain in chronic insomnia and anxiety disorder: a combined structural and functional fMRI study
Minghe Xu,
Bo Li,
Shuang Wang
et al.
Abstract:BackgroundChronic insomnia disorder (CID) is usually associated with Generalized Anxiety Disorder (GAD), which may change brain structure and function. However, the possible brain markers, imaging characteristics, and pathophysiology are unknown.ObjectiveTo look at the probable brain markers, imaging characteristics, and pathogenesis of CID in combination with GAD.MethodsA total of 57 patients with CID concomitant GAD and 57 healthy controls (HC) were enrolled. Voxel-based morphometry (VBM) and functional conn… Show more
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