The Bone Scan

Brenner, Arnold; Koshy, June; Morey, Jose; Lin, Chin-Chu; DiPoce, Jason

doi:10.1053/j.semnuclmed.2011.07.005

Cited by 140 publications

(105 citation statements)

References 72 publications

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“…Los osteoblastos forman la matriz osteoide que posteriormente será mineralizada por los cristales de hidroxiapatita. El metilendifosfonato (99mTc-MDP) se une mediante quimioadsorción a los cristales de hidroxiapatita en función de dos situaciones: el flujo sanguíneo y la actividad osteoblástica 6,7 . Conforme la NCCN, el gammagrama óseo está indicado en pacientes con niveles de APE > 20 ng/ml, Gleason ≥ 8, T3, T4 o T2 si APE > 10 ng/ml, o si presentan síntomas 8 .…”

Section: Metilendifosfonatounclassified

Radiotrazadores empleados en medicina nuclear para el diagnóstico y seguimiento del cáncer de próstata

García-Pérez¹,

Medina-Ornelas²

2022

GAMO

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Resumen El cáncer de próstata (CP) es la causa más común de cáncer en hombres a nivel mundial. Actualmente, la imagen en el CP ha tomado una gran importancia para la estadificación, reestadificación, selección del tratamiento y evaluación de la recurrencia. La imagen molecular con tomografía por emisión de positrones (PET) ha permitido un enfoque personalizado para estos propósitos. Además de estas necesidades clínicas, existe una creciente visión y reto para las nuevas técnicas de imagen molecular, no sólo para detectar la enfermedad metastásica, sino también para proporcionar información importante acerca de la biología tumoral, el pronóstico y, uno de los retos más grandes de las técnicas de imagen no radioisotópicas, la detección de recurrencia en pacientes con niveles bajos de antígeno prostático específico (APE). (creativecommons.org/licenses/by-nc-nd/4.0/). ARTÍCULO DE REVISIÓNRadiotrazadores empleados en medicina nuclear para el diagnóstico y seguimiento del cáncer de próstata

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Section: Metilendifosfonatounclassified

Radiotrazadores empleados en medicina nuclear para el diagnóstico y seguimiento del cáncer de próstata

García-Pérez¹,

Medina-Ornelas²

2022

GAMO

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“…Bone scan shows a higher sensitivity compared to radiographic images. Five percent change in bone turnover can be detected on bone imaging [5], while 30%∼50% of mineral loss precedes radiographic changes on plain X-ray and CT images [13]. Bone uptake is increased for both osteoblastic and osteolytic process, such as tiny amount of bone destruction with osteoblastic healing process.…”

Section: Main Subjectsmentioning

confidence: 99%

“…Planar bone scan has many advantages in localizing active disease process, identifying increased physiologic activity, and evaluating pain, but still needs to overcome poor image resolution and lower specificity. Therefore, adding the information of perfusion status, three phase bone scan may enhance specificity in evaluation of inflammation and infection [5,6]. Single photon emission computed tomography/computed tomography (SPECT/CT) provides three-dimensional (3D) information (axial, coronal and sagittal images), and its ability to superimpose the physiologic data obtained by SPECT imaging on the detailed anatomy of CT improves the diagnostic performance [7].…”

Section: Introductionmentioning

confidence: 99%

Nuclear Medicine Imaging in Rheumatic Diseases

Choi

Kim

2017

J Rheum Dis

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The rapid development of medical imaging technologies has greatly enhanced the utility of nuclear medicine imaging modalities over the last decade. Hybrid imaging technology merging computed tomography (CT) with single-photon emission computed tomography (SPECT) or positron emission tomography (PET) allows superimposing the physiologic data obtained by SPECT or PET on the detailed anatomy of CT, yielding a better understanding of the disease status and improving diagnostic performance. However, the conventional whole body bone scan and three phase bone scan still have their own distinct role as diagnostic imaging, reflecting the changes of bone metabolism in benign and malignant diseases, including rheumatic diseases. A review of each nuclear medicine imaging technique and clinical applications in various conditions of rheumatic diseases will be presented in this article. (J Rheum Dis 2017;24:4-13)

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“…Imaging physiology has many values, including its ability to detect pathology earlier than anatomical imaging in some instances (Brenner et al, 2012). When assessing pathology it is often necessary to image physiology as well as anatomy, so that a full understanding can be reached about the disease and how it might be managed.…”

Section: What Is Nuclear Medicine?mentioning

confidence: 99%