The Bone Marrow of Normal Dogs

Reference Values for the Bone Marrow Aspirates in Adult Dogs

“…In some instances, the mean myeloid count exceeded 60% (Rekers and Coulter, 1948;Penny, 1974). Only a small number of investigators reported results similar to our data (Mulligan, 1941;Meyer and Bloom, 1943;Saar and Ulrich, 1975). With the higher myeloid count there was a consequent reduction particularly in the erythroid lineage.…”

“…Considering the wide normal range found in the present study, the usually small number of animals investigated by other authors might contribute to the discrepancy in lymphocyte proportion reported. The percentage of plasma cells found in this study was higher than in all other studies that considered this cell type in the differential count (Meyer and Bloom, 1943;Rekers and Coulter, 1948;Horn et al, 1953;Melveger et al, 1969;Penny, 1974;Saar and Ulrich, 1975). Only Hoff et al (1985) found median values (2.05%) that approximately corresponded to our results.…”

“…The low proportion of monocytes found in the marrow of healthy dogs in our study confirms the results of most other studies that reported mean values between 0 and 1% (Van Loon and Clark, 1943;Rekers and Coulter, 1948;Horn et al, 1953;Melveger et al, 1969;Saar and Ulrich, 1975;Coles, 1986;Jain, 1986). However, higher values were published by Alexandrov (1928) and Meyer and Bloom (1943). Alexandrov (1928) reported a median percentage of 10.4% monocytes, but he questioned his own results suggesting a possible misinterpretation of the marrow films.…”

“…Comparison of the results of the present study with the results reported in the literature for bone marrow aspirates of healthy adult dogs is difficult because of the different nomenclature as well as differences in method of performing the differential count and statistical analysis. For example, some studies completely excluded plasma cells, cells of the mononuclear phagocytic system and/or megakaryocytes from the differential count because of their relatively low percentage (Alexandrov, 1928; Stasney and Higgins, 1937; Mulligan, 1941; Meyer and Bloom, 1943; Rekers and Cloulter, 1948; Penny, 1974; Coles, 1986; Jain 1986). In most studies, data are only given as mean (± standard deviation/± standard error) or median (minimum–maximum) values.…”

Blood

“…593 The esti¬ mated life of the erythrocyte was calculated by Davis 594 as twenty days for the dog and twentytwo days for the rabbit. 593 The esti¬ mated life of the erythrocyte was calculated by Davis 594 as twenty days for the dog and twentytwo days for the rabbit.…”