In this paper, we study the regular geometric behavior of the mean curvature flow (MCF) of submanifolds in the standard Gaussian metric space (R m+p , e −|x| 2 /m g) where (R m+p , g) is the standard Euclidean space and x ∈ R m+p denotes the position vector. Note that, as a special Riemannian manifold, (R m+p , e −|x| 2 /m g) has an unbounded curvature. Up to a family of diffeomorphisms on M m , the mean curvature flow we considered here turns out to be equivalent to a special variation of the "conformal mean curvature flow " which we have introduced previously. The main theorem of this paper indicates, geometrically, that any immersed compact submanifold in the standard Gaussian space, with the square norm of the position vector being not equal to m, will blow up at a finite time under the mean curvature flow, in the sense that either the position or the curvature blows up to infinity; Moreover, by this main theorem, the interval [0, T ) of time in which the flowing submanifolds keep regular has some certain optimal upper bound, and it can reach the bound if and only if the initial submanifold either shrinks to the origin or expands uniformly to infinity under the flow. Besides the main theorem, we also obtain some other interesting conclusions which not only play their key roles in proving the main theorem but also characterize in part the geometric behavior of the flow, being of independent significance.