The Blood in Cases of Unexplained Gastric Anacidity 1

Ws, Polland

doi:10.1172/jci100523

Cited by 3 publications

(1 citation statement)

References 12 publications

(10 reference statements)

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“…The pH levels cannot be correlated with the gastroscopic picture, the presence or absence of a secretory depressant in the gastric secretions, or the presence or absence of anemia. Polland (15) likewise attaches no significance to cause of anacidity.…”

Section: Discussionmentioning

confidence: 99%

Studies on Anacidity: The Hydrogen-Ion Concentration of the Gastric Secretion, the Gastroscopic Appearance of the Gastric Mucosa, and the Presence of a Gastric Secretory Depressant in Patients With Anacidity

Kirsner¹,

Nutter²,

Palmer³

1940

J. Clin. Invest.

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Section: Discussionmentioning

confidence: 99%

Studies on Anacidity: The Hydrogen-Ion Concentration of the Gastric Secretion, the Gastroscopic Appearance of the Gastric Mucosa, and the Presence of a Gastric Secretory Depressant in Patients With Anacidity

Kirsner¹,

Nutter²,

Palmer³

1940

J. Clin. Invest.

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ABSORPTION of IRON from the Gastrointestinal Tract

Grace

Doig

Wolff

et al. 1954

The American Journal of Clinical Nutrition

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The gastric secretion in anaemia

Ogilvie¹

1935

Archives of Disease in Childhood

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It is well known that anaemia of the Addisonian type is accompanied by an absence of free hydrochloric acid from the gastric juice.In so-called secondary anaemia Davies' found that in the gastric juice there was excess of mucus, low peptic activity and frequently a fixed pH in contrast with the absence of mucus and peptic activity and complete fixation of the pH in pernicious anaemia. Hartfall and Witts' pointed out that in simple -achlorhydric anaemia t-he total chlorine and peptic activity were low when there was a deficient amount of intrinsic factor. Recently Hartfall' has stated that in the same individual free acid may be secreted at one time and not at another. He also considered that the data obtained from infants were unreliable owing to the numerous inhibitory factors likely to interfere with gastric secretion. In twenty-six adult patients with unexplained achlorhydria Polland' failed to find any significant variation from normal in the haemoglobin value and red cell count; he therefore concluded that anacidity per se did not tend to the production of anaemia. Bloomfield and Keefer' as a result of their investigations into gastric secretion in adults decided that anaemia, other than the pernicious type, had little or no influence on the secretion of gastric juice. Hawksley, Lightwood and Bailey6 in thirteen children under ten years of age with simple iron-deficiency anaemia found achlorhydria in twelve, and consider that achlorhydria may be a causal factor. In the literature-there are few' other studies in children of the association of anaemia with defective gastric secretion.During the course of an investigation into the gastric secretion in children, the following results were obtained. Thirty-four anaemic children, twenty-two boys and twelve girls, were examined; the ages varied between five months and eleven years. The method employed in examining the gastric secretion has been described in previous papers7. In children, as in adults, there is wide variation in the concentration of the hydrochloric acid in the gastric juice but for purposes of classification any readings of an acidity above 50 c.c. or below 12 c.c. I" per cent. were considered to indicate hyper-or hypochlorhydria respectively.

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The Blood in Cases of Unexplained Gastric Anacidity 1

Cited by 3 publications

References 12 publications

Studies on Anacidity: The Hydrogen-Ion Concentration of the Gastric Secretion, the Gastroscopic Appearance of the Gastric Mucosa, and the Presence of a Gastric Secretory Depressant in Patients With Anacidity

Studies on Anacidity: The Hydrogen-Ion Concentration of the Gastric Secretion, the Gastroscopic Appearance of the Gastric Mucosa, and the Presence of a Gastric Secretory Depressant in Patients With Anacidity

ABSORPTION of IRON from the Gastrointestinal Tract

The gastric secretion in anaemia

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