The Blood Group Antibody “Good,” 1966 I. Clinical Aspects, Routine Serologic Studies, Further Search for Antigen and Antibodies

Abstract

The Good family, in which the husband's red blood cells contain a private antigen (Good) responsible for the development of severe erythroblastosis fetalis in four infants, has had two additional infants since the original reports in 1960 and 1961. The latest pregnancy, which terminated in 1965, permitted further evaluation of both the Good antigen and anti‐Good. The antibody has been found in 0.3% of sera of a random donor population (eight examples in 2,718 donors). No additional example of the antigen has been found in 2,382 random donors. Spectrophotometric analysis of amniotic fluid was used in management of the latest pregnancy, which resulted in a normal unaffected infant.