The biotechnological production of xanthan on vegetable oil industry wastewaters. Part I: Modelling and optimization

Bajic, Z Bojana; Vučurović, Damjan; Dodic, N Sinisa; Rončević, Zorana; Grahovac, Jovana; Dodic, M Jelena

doi:10.2298/ciceq160430048b

Cited by 5 publications

(5 citation statements)

References 27 publications

(32 reference statements)

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“…Response surface methodology (RSM) is one of the most frequently used optimization methods in chemical and biochemical engineering (Assis et al 2014;Ayyalusamy and Mishra 2018;Bajić et al 2017;Grahovac et al 2014;Rončević et al 2019a). This efficient approach has been widely applied in various studies because the process of interest can be defined and explained by adequate mathematical equations.…”

Section: Introductionmentioning

confidence: 99%

Optimisation of xanthan production on glycerol-based medium using response surface methodology

Rončević

Bajić

Vlajkov

et al. 2020

Braz. J. Chem. Eng.

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Xanthan is one of the most important biopolymers characterised by a high commercial value. Since the availability of essential nutrients influences its biosynthesis, the aim of this study was the optimisation of carbon, organic and inorganic nitrogen content in glycerol-based medium employing response surface methodology. The cultivation of strain Xanthomonas campestris ATCC 13951 was carried out under appropriate conditions on media with glycerol, peptone and ammonium-nitrate formulated according to Box-Behnken design (3 3), while the desirability function approach was used for determination of optimal nutrient levels. The final model predicts that the maximal amount of xanthan (12.95 g/L) is produced when the initial contents of glycerol, peptone and ammonium-nitrate in the medium are 32.96 g/L, 0.55 g/L and 0.73 g/L, respectively. To minimize the residual nutrient content and therefore the costs of effluent processing, additional optimisation was performed. In order to validate the optimisation model developed and examine the bioprocess success with crude glycerol as the sole carbon source, additional experiments were performed. The results represent reliable information for further investigations.

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Section: Introductionmentioning

confidence: 99%

Optimisation of xanthan production on glycerol-based medium using response surface methodology

Rončević

Bajić

Vlajkov

et al. 2020

Braz. J. Chem. Eng.

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“…Additionally, the value of nitrogen conversion using media based on bioethanol production effluents ranged between 44.01-54.15 %, whereas the value of phosphorus conversion ranged between 65.47-74.58%. The obtained conversion values of carbon source, nitrogen and phosphorus are particularly significant when considering that nutrients that are not utilized during biosynthesis remain in the wastewater and pose both economic and environmental losses (Bajić et al, 2017).…”

Section: Resultsmentioning

confidence: 99%

“…Therefore, it is important to find a more costeffective and abundant substrate in order to increase the efficiency of this bioprocess (Lopez and Ramos-Cormenzana, 1996). Based on a number of previous studies, it can be concluded that xanthan production is possible using effluents from the food industry and agricultural waste as a basis of the cultivation media (Bajić et al, 2017).…”

Section: Introductionmentioning

confidence: 99%

Liquid effluents of bioethanol production from various raw materials as media for xanthan biosynthesis

Bajić¹,

Dodić²,

Puškaš³

et al. 2018

J Proc Ener Agri

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The purpose of this paper is to examine the viability of using liquid effluents of bioethanol production from molasses, corn and a mixture of waste starch raw materials as a basis of the cultivation medium for the biotechnological production of xanthan using Xanthomonas campestris ATCC 13951. The dynamics of basic macronutrient consumption was used to monitor the course of xanthan biosynthesis, whereas the possibility of biosynthesis was confirmed on the basis of the rheological parameters of the cultivation broth. The success of biosynthesis was assessed according to the values of xanthan content and conversion to xanthan, which ranged from 8.78 g/L to 11.16 g/L and from 58.13 % to 73.24 % respectively when using the cultivation media based on liquid effluents of bioethanol production from different raw materials.

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“…According to published data, all tested agents with an inhibition zone radius larger than 11 mm could be considered as significantly antagonistic [22]. On the other hand, on industrial scale, the content of residual carbon lower than 5 g L -1 indicates the completion of the bioprocess [23]. Therefore, the amount of residual glycerol lower than 5 g L -1 and inhibition zone diameters larger than 22 mm were defined as the specific goal of optimization.…”

Section: Multiobjective Genetic Algorithm Optimizationmentioning

confidence: 99%

Optimization of Streptomyces hygroscopicus Cultivation Parameters in a Lab‐scale Bioreactor

et al. 2021

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The production of different metabolites by Streptomyces spp. is directly influenced by oxygen transfer. On the other hand, intensive agitation and aeration may have negative effects on productivity due to high shear stress which causes damage to cells. Therefore, the aim of this study was multiobjective optimization of main scale‐up parameters using genetic algorithms. Between diverse solutions, an increase in aeration rate leads to the maximal production of biocontrol agents effective against storage apple pathogens of the Alternaria and Fusarium genera. Simultaneously, an increase in aeration rate enables the usage of a lower stirrer speed and significantly shorter bioprocess duration which supports the profitability of a defined production.

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The biotechnological production of xanthan on vegetable oil industry wastewaters. Part I: Modelling and optimization

Cited by 5 publications

References 27 publications

Optimisation of xanthan production on glycerol-based medium using response surface methodology

Optimisation of xanthan production on glycerol-based medium using response surface methodology

Liquid effluents of bioethanol production from various raw materials as media for xanthan biosynthesis

Optimization of Streptomyces hygroscopicus Cultivation Parameters in a Lab‐scale Bioreactor

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