The Biology of Experimental Human Cutaneous Moniliasis (Candida Albicans)

Incidence and distribution of Candida species isolated from human skin in Jordan

“…The isolation of such Candida species does not prove the diagnosis of cutaneous candidosis and no marked differences in their clinical picture could be observed. Cutaneous lesions have been produced on the skin of experimental animal and/or human volunteers with some strains of C. krusei [23], C. parapsilosis [29], and C. tropicalis [23], as well as C. albicans [15].…”

‘Decubital candidosis’: a study of 26 cases

“…Our histopathological findings were very similar to those obtained by Maibach and Kligman in their seminal study under experimental conditions 7 . These authors performed serial biopsies of skin previously inoculated with candida and then occluded with plastic bands.…”

Cytokine expression induced by Candida albicans in a model of cutaneous candidosis based on reconstituted human epidermis

“…Cytokine expression patterns observed in reconstituted human epidermis after treatment with allergic or toxic agents, or both, are similar to those seen after infection with C. albicans. In previous studies, the skin reactions seen in experimental C. albicans infection have been explained as a sort of biological contact dermatitis of the primary irritant or allergic type [22][23][24][25]. The present study found morphological alterations and a cytokine profile of reconstituted human epidermis induced by C. albicans infection, which are similar to that found in irritant/ allergic contact dermatitis [18].…”