The Biological Role of Vitamins in Athletes’ Muscle, Heart and Microbiota

Brancaccio, Mariarita; Mennitti, Cristina; Cesaro, Arturo; Fimiani, Fabio; Vano, Martina; Gargiulo, Biagio; Caiazza, Martina; Amodio, Federica; Coto, Iolanda; D’Alicandro, Giovanni; Mazzaccara, Cristina; Lombardo, Barbara; Pero, Raffaela; Terracciano, Daniela; Limongelli, Giuseppe; Calabrò, Paolo; D’Argenio, Valeria; Frisso, Giulia; Scudiero, Olga

doi:10.3390/ijerph19031249

Cited by 38 publications

(42 citation statements)

References 155 publications

(172 reference statements)

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“…A further limitation is the lack of a nutritional table of the subjects. It would have been an important finding as some authors suggest that low levels of magnesium and zinc promote excitotoxicity [ 51 , 52 ]. Another limitation is the lack of a control group that would have helped to strengthen our results.…”

Section: Discussionmentioning

confidence: 99%

Can the Combination of Rehabilitation and Vitamin D Supplementation Improve Fibromyalgia Symptoms at All Ages?

Scaturro

Vitagliani

Tomasello

et al. 2022

JFMK

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Several studies have indicated a correlation between vitamin D deficiency and widespread chronic pain syndromes, such as fibromyalgia. During this study, the effect of supplementation with vitamin D in association with physical exercise in patients with fibromyalgia was evaluated, in terms of improvement of pain, functional capacity and quality of life, also evaluating the presence of any differences in age. A single-center, observational, comparative study was conducted in 80 fibromyalgia patients. They are randomized into 2 groups: Group A, consisting of patients ≤50 years; and group B, consisting of patients >50 years. Both received weekly supplementation with 50,000 IU cholecalciferol for 3 months in association with a rehabilitation protocol. Patients were assessed at enrollment (T0), 3 months (T1), and 6 months (T2) from the initial assessment with blood vitamin D dosage and administration of rating scales (NRS, FIQ, and SF-12). From the comparison between the two groups, we have seen that in young people, supplementation with high-dose vitamin D improves short-term musculoskeletal pain and long-term functional capacity. Conversely, musculoskeletal pain and long-term quality of life improve in the elderly. Supplementing with high doses of vitamin D in fibromyalgia patients improves the quality of life and pain in the elderly and also the functional capacity in the young.

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Section: Discussionmentioning

confidence: 99%

Can the Combination of Rehabilitation and Vitamin D Supplementation Improve Fibromyalgia Symptoms at All Ages?

Scaturro

Vitagliani

Tomasello

et al. 2022

JFMK

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“…The main objective of our work was to assess whether the athletes studied had serum vitamin D3 deficiency. It should be emphasized that the vitamin D3 status in athletes is an important research problem which, on the one hand, indicates the fundamental role of vitamin D3 supplementation in physical activity (41,42) and, on the other hand, proves the commonly observed vitamin D3 insufficiency/deficiency in athletes (43). We confirmed that in 68% of our study athletes the average baseline 25(OH)D concentration was below 30 ng/mL, which can be classified as insufficiency of vitamin D3.…”

Section: Discussionmentioning

confidence: 99%

Effect of Vitamin D3 Supplementation on Interleukin 6 and C-Reactive Protein Profile in Athletes

Brzeziański

Pastuszak-Lewandoska

Migdalska-Sęk

et al. 2022

J Nutr Sci Vitaminol

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Vitamin D3 has a preventive, anti-inflammatory effect. However, there are still few studies linking the effects of athlete training to vitamin D3 supplementation and the immune response. The study evaluated the impact of vitamin D3 supplementation on interleukin 6 (IL-6) release during physical exercise in relation to C-reactive protein (CRP) levels in healthy male athletes. Twenty-five soccer players were divided into two groups-with (GS) and without (GN) vitamin D3 supplementation in a dose of 20,000 IU twice a week for 8 wk (about 6,000 IU/d). At the baseline (T1) and at the end (T2) of the training cycle serum concentrations of 25-hydroxyvitamin D [25(OH)D], IL-6 and CRP were measured. In the GS group, we observed a significant increase in 25(OH)D concentration (p50.004), and non-significantly increased levels (p.0.05) of IL-6 and CRP. At the baseline, CRP in the supplemented athletes who had suboptimal vitamin D3 concentration in T1 (GSO) was significantly higher than in those with an optimal baseline vitamin D3 level (GO) (p50.028). However, in GO in T2, a non-significant trend of negative correlation (p50.055) between 25(OH)D concentration and IL-6 level was found. In the total study group (TG), a statistically significant (p50.021) negative correlation in T1 was observed between 25(OH)D and CRP. However, our results do not support the immune-modulatory effect of vitamin D3 supplementation in a dose of 6,000 IU/d in athletes, in relation to IL-6 production and its subsequent stimulatory effect on CRP releasing.

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“…Vitamins and minerals are the crucial micronutrients needed by the body to regulate multiple functions and the metabolism of the body ( 273 , 274 ). Vitamins and minerals are naturally present in plants.…”

Section: Methodsmentioning

confidence: 99%

Botanicals: A promising approach for controlling cecal coccidiosis in poultry

Saeed

Alkheraije

2023

Front. Vet. Sci.

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Avian species have long struggled with the problem of coccidiosis, a disease that affects various parts of the intestine, including the anterior gut, midgut, and hindgut. Among different types of coccidiosis, cecal coccidiosis is particularly dangerous to avian species. Chickens and turkeys are commercial flocks; thus, their parasites have remained critical due to their economic importance. High rates of mortality and morbidity are observed in both chickens and turkeys due to cecal coccidiosis. Coccidiostats and coccidiocidal chemicals have traditionally been added to feed and water to control coccidiosis. However, after the EU banned their use because of issues of resistance and public health, alternative methods are being explored. Vaccines are also being used, but their efficacy and cost-effectiveness remain as challenges. Researchers are attempting to find alternatives, and among the alternatives, botanicals are a promising choice. Botanicals contain multiple active compounds such as phenolics, saponins, terpenes, sulfur compounds, etc., which can kill sporozoites and oocysts and stop the replication of Eimeria. These botanicals are primarily used as anticoccidials due to their antioxidant and immunomodulatory activities. Because of the medicinal properties of botanicals, some commercial products have also been developed. However, further research is needed to confirm their pharmacological effects, mechanisms of action, and methods of concentrated preparation. In this review, an attempt has been made to summarize the plants that have the potential to act as anticoccidials and to explain the mode of action of different compounds found within them.

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The Biological Role of Vitamins in Athletes’ Muscle, Heart and Microbiota

Cited by 38 publications

References 155 publications

Can the Combination of Rehabilitation and Vitamin D Supplementation Improve Fibromyalgia Symptoms at All Ages?

Can the Combination of Rehabilitation and Vitamin D Supplementation Improve Fibromyalgia Symptoms at All Ages?

Effect of Vitamin D3 Supplementation on Interleukin 6 and C-Reactive Protein Profile in Athletes

Botanicals: A promising approach for controlling cecal coccidiosis in poultry

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