The biological false positive reaction to serological tests for syphilis

The VDRL test in a blood transfusion service.

“…As there are less female donors on the panel than male donors, the finding of slightly more female donors with BFP results confirms previous statements that BFP results are commoner in females than males (Gamer, 1970). In this present series, there is a somewhat larger number of young women than expected from previous evidence (Beal, 1965), and prolonged involvement with blood donation cannot be invoked as an explanation of the BFP result in at least some of these donors, since 46 of the 120 R. W. Beal and D. J. Merry female donors are under 25 years of age and would have been involved with blood donation only since the age of 18 at the earliest.…”

An uncertain association between influenza season, recent influenza vaccination campaigns, and unconfirmed repeat reactive syphilis serology assay results in Canadian blood donors

“…Similar seasonal trends in repeat reactive syphilis serology results that were unable to be confirmed have been noted by other blood operators (Personal communication Dr. Gilles Delage [Héma-Québec] and Dr. Phillip Williamson [Creative Testing Solutions]). Although vaccination has been linked to false-positive syphilis serology testing for decades, 6 there is no evidence for deferring blood donors with a recent history of influenza vaccine.…”

Issues of serological diagnosis of syphilis. Interpretation of the results of serological tests

“…БЛПР, регистрируемые у лиц, не страдающих сифилисом, с помощью НТТ, возможны при ВИЧ-инфекции, гепатите C, беременности, в пожилом возрасте пациентов, при тяжелой соматической па-тологии (в том числе эндокринной, онкопатологии, заболеваниях сердечно-сосудистой системы, желу-дочно-кишечного тракта, легких, при некоторых дерматозах) [8][9][10][11][12][13][14][15][16].…”