The biological behavior and clinical outcome of pituitary adenoma are affected by the microenvironment
Yuhe Li,
Xiufang Ren,
Wei Gao
et al.
Abstract:BackgroundPituitary adenoma is one of the most common brain tumors. Most pituitary adenomas are benign and can be cured by surgery and/or medication. However, some pituitary adenomas show aggressive growth with a fast growth rate and are resistant to conventional treatments such as surgery, drug therapy, and radiation therapy. These tumors, referred to as refractory pituitary adenomas, often relapse or regrow in the early postoperative period. The tumor microenvironment (TME) has recently been identified as an… Show more
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