The educational gap for which science is not taught to managers, and management is not taught to scientists, is a significant obstacle to a company's success also in the bioeconomy field. Companies worldwide eagerly seek for new managers, researchers and technologists owning new knowledge and skills in topics spanning from circular production processes through new energy technologies and green chemistry. Most employers, however, have difficulty recruiting qualified professionals due to the shortage of qualified professionals. This shortage includes bioeconomy managers capable to successfully lead bioeconomy companies. Shaping the managers of successful bioeconomy companies, we argue in this study, requires to transfer a closer understanding of the nature of bioeconomy companies and their competitive landscape, as well as identifying the main guiding principles for managing these organizations.