The Biocompatibility Manifesto: Biocompatibility for the Twenty-first Century

Ratner, Buddy D.

doi:10.1007/s12265-011-9287-x

Cited by 123 publications

(85 citation statements)

References 27 publications

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“…Disagreeing with Ratner 15 that studied the coating of implants and concluded that a greater angiogenesis occurs when the pores on the surface of the implants are between 30-40 μm with less collagen deposition, in this study the pores measured 50-250 μm in the textured group and 250-350 μm in polyurethane group, and was obtained in both groups and in all subgroups, discrete angiogenesis with a significant deposition of collagen which was larger in the polyurethane group.…”

Section: Evaluation Of the Total And Percentage Areas Of Collagen Typsupporting

confidence: 56%

“…According to Ratner 15 Haddad Filho et al 16 after comparing silicone implants with a textured surface and coated PTFE-E, it was concluded that both groups induced a weak foreign body reaction, which was higher in textured group. Disagreeing with this author, in this study the foreign body reaction was absent in the textured group at all subgroups.…”

Section: Evaluation Of Foreign Body Reactionmentioning

confidence: 99%

“…Ratner 15 , the capsule formed around the implants is an attempt by the body to isolate it, which is a matter of incompatibility.…”

Section: Histological Aspectsmentioning

confidence: 99%

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Histological evaluation of capsules formed by silicon implants coated with polyurethane foam and with a textured surface in rats

Silva¹,

Ribas-Filho²,

Czeczko³

et al. 2016

Acta Cir. Bras.

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PURPOSE:To assess the capsules formed by silicone implants coated with polyurethane foam and with a textured surface. METHODS:Sixty-four Wistar albinus rats were divided into two groups of 32 each using polyurethane foam and textured surface. The capsules around the implants were analyzed for 30, 50, 70 and 90 days. Were analyzed the following parameters: foreign body reaction, granulation tissue, presence of myofibroblasts, neoangiogenesis, presence of synovial metaplasia, capsular thickness, total area and collagen percentage of type I and III, in capsules formed around silicone implants in both groups. RESULTS:The foreign body reaction was only present in the four polyurethane subgroups. The formation of granulation tissue and the presence of myofibroblasts were higher in the four polyurethane subgroups. Regarding to neoangiogenesis and synovial metaplasia, there was no statistical difference between the groups. Polyurethane group presented (all subgroups) a greater capsule thickness, a smaller total area and collagen percentage of type I and a higher percentage area of type III, with statistical difference. CONCLUSION:The use of polyurethane-coated implants should be stimulated by the long-term results in a more stable capsule and a lower incidence of capsular contracture, despite developing a more intense and delayed inflammatory reaction in relation to implants with textured surface.

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Section: Evaluation Of the Total And Percentage Areas Of Collagen Typsupporting

confidence: 56%

Section: Evaluation Of Foreign Body Reactionmentioning

confidence: 99%

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Histological evaluation of capsules formed by silicon implants coated with polyurethane foam and with a textured surface in rats

Silva¹,

Ribas-Filho²,

Czeczko³

et al. 2016

Acta Cir. Bras.

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“…These challenges are still there. Blood compatibility catastrophe [19,20] is still exactly that, [21] modern interfaces are as simplistic as ever (as opposed to intelligent/self-healing/ self-replicating), and any discussion of interfacial water brings smiles to the faces of most scientists. Yet the community appears to be melting in the process of searching for a new identity.…”

Section: E D I T O R I a L Open Accessmentioning

confidence: 99%

The new faces of biointerfaces?

Reviakine

2013

Biointerphases

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“…In this context, biocompatibility refers to the ability to perform with an appropriate host response in the given application [17][18][19]. For this purpose, hydrogels are ideally suited since they are able to absorb more than 70 wt% of their dry weight in water [8].…”

Section: Introductionmentioning

confidence: 99%

Bioactive 3D-Shaped Wound Dressings Synthesized from Bacterial Cellulose: Effect on Cell Adhesion of Polyvinyl Alcohol Integrated In Situ

Osorio

Velásquez-Cock

Múnera

et al. 2017

International Journal of Polymer Science

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We investigated wound dressing composites comprising fibrils of bacterial cellulose (BC) grown by fermentation in the presence of polyvinyl alcohol (PVA) followed by physical crosslinking. The reference biointerface, neat BC, favoured adhesion of fibroblasts owing to size exclusion effects. Furthermore, it resisted migration across the biomaterial. Such effects were minimized in the case of PVA/BC membranes. Therefore, the latter are suggested in cases where cell adhesion is to be avoided, for instance, in the design of interactive wound dressings with facile exudate control. The bioactivity and other properties of the membranes were related to their morphology and structure and considered those of collagen fibres. Bioactive materials were produced by simple 3D templating of BC during growth and proposed for burn and skin ulcer treatment.

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The Biocompatibility Manifesto: Biocompatibility for the Twenty-first Century

Cited by 123 publications

References 27 publications

Histological evaluation of capsules formed by silicon implants coated with polyurethane foam and with a textured surface in rats

Histological evaluation of capsules formed by silicon implants coated with polyurethane foam and with a textured surface in rats

The new faces of biointerfaces?

Bioactive 3D-Shaped Wound Dressings Synthesized from Bacterial Cellulose: Effect on Cell Adhesion of Polyvinyl Alcohol Integrated In Situ

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