The Biochemistry of the Functional Psychoses

Association of catechol‐O‐methyltransferase variants with loudness dependence of auditory evoked potentials

“…An enhancement of dopaminergic transmission leads to an increased utilization and increased tissue levels of 5-HT in areas innervated by the dorsal raphe nucleus (Grabowska et al, 1973;Lee and Geyer, 1984;Lee, 1987). Both transmitter systems play an important role in the currently discussed models of schizophrenic disorders (Weil-Malherbe, 1967;Faurbye, 1968;Farley et al, 1980;Bleich et al, 1988;Owen and Simpson, 1994).…”