The bidirectional interaction between antidepressants and the gut microbiota: are there implications for treatment response?
Gianluca Borgiani,
Chiara Possidente,
Chiara Fabbri
et al.
Abstract:This review synthesizes the evidence on associations between antidepressant use and gut microbiota composition and function, exploring the microbiota’s possible role in modulating antidepressant treatment outcomes. Antidepressants exert an influence on measures of gut microbial diversity. The most consistently reported differences were in β-diversity between those exposed to antidepressants and those not exposed, with longitudinal studies supporting a potential causal association. Compositional alterations in … Show more
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