The Best of 2018 in the Annals of Allergy, Asthma, and Immunology

Abstract

The editors of the Annals of Allergy, Asthma, and Immunology considered more than 750 submissions for publication in 2018. From that number, we accepted 323 articles, letters, and other features to be included in the 12 issues of the 2018 Annals. Every feature was carefully scrutinized before acceptance, and there were multiple articles that were acceptable but were not used because of space constraints (ie, we do not have room to publish all of the acceptable manuscripts we received). Accordingly, the 323 are already the "best" of the submissions that were submitted last year. We are grateful to all the authors who submitted and those whose articles were published. At the end of the year, all the Annals editors provided their assessments of features published in the Annals from various areas of our specialty based on the individual interests and expertise of the editors. The results of these efforts produced mentions of the "best of the best" that we want to make sure you, our readership, had the opportunity to see, and we hope, read. The following is written with this aim in mind. Atopic DermatitisDuring the past year, there have been several highlighted themes on atopic dermatitis (AD) published in the Annals. Importantly, the multidimensional burden of AD was well documented, 1 including the effect of AD on quality of life, low self-esteem, increased sick days, reduced physical activity, and adverse effects

Alteration of Allergen Fold of Bos d 5 into a Hypoallergenic Vaccine for Immunotherapy of Cow’s Milk Allergy

“…The symptoms of CMA range from allergic asthma, diarrhea, cystitis to other severe and life-threatening symptoms [3,4]. Bos d 5, also named as β-lactoglobulin, is the main cow's milk protein (CMP) and makes up approximately 10% of the CMPs [5]. More than 60% of the patients with CMA are sensitized to this protein [6].…”