The beneficial effects of neutrophil elastase inhibitor on gastrointestinal dysfunction in sepsis
Jia‐Kui Sun,
Jing‐Jing Li,
Yi‐Hang Deng
et al.
Abstract:To investigate the effects of neutrophil elastase inhibitor (sivelestat sodium) on gastrointestinal function in sepsis. A reanalysis of the data from previous clinical trials conducted at our center was performed. Septic patients were divided into either the sivelestat group or the non‐sivelestat group. The gastrointestinal dysfunction score (GIDS), feeding intolerance (FI) incidence, serum levels of intestinal barrier function and inflammatory biomarkers were recorded. The clinical severity and outcome variab… Show more
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