The beneficial effects of almond (Prunus amygdalus Batsch) hull on serum lipid profile and antioxidant capacity in male rats

Safarian, Soheil; Azarmi, Yadollah; Jahanban-Esfahlan, Ali; Jahanban-Esfahlan, Hasan

doi:10.3906/sag-1504-127

Cited by 14 publications

(6 citation statements)

References 49 publications

(84 reference statements)

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“…Nuts are described as a leading source of phenolic compounds with high antioxidant activity, particularly walnuts, pecans, pistachios, hazelnuts, almonds, and peanuts [28,88,89,90,91,92,93,94,95,96,97]. The nut of the Persian walnut is essential in human nutrition, because it contains the valuable kernel, which shows high nutritional capacity due to high levels of unsaturated fatty acids, digestible proteins, phenolic compounds, and dietary fiber [21,98,99].…”

Section: The Health Benefits Of Walnutsmentioning

confidence: 99%

“…Today, some spectroscopic and colorimetric methods are available for the measurement and determination of the antioxidant content of different plant-based materials [140]. According to the ample evidence, there is a relation between the antioxidant content and its bioactivity [28,89,93,94,95,141]. In this respect, the TPC, TFC, total flavanol content (TFAC), total flavonol content (TFOC), total hydroxybenzoic acid content (THBAC), total hydroxycinnamic acid content (THCAC), TCTC, total ellagitannin content (TETC), and total gallotannin content (TGTC) of the walnut green husk were determined in different investigations, and the reported values are summarized in Table 1.…”

Section: Antioxidant Content and Radical Scavenging Activity Of Wamentioning

confidence: 99%

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A Comprehensive Review on the Chemical Constituents and Functional Uses of Walnut (Juglans spp.) Husk

Jahanban-Esfahlan

Ostadrahimi

Tabibiazar

et al. 2019

IJMS

146

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The walnut (Juglans spp.) is an appreciated nut that belongs to the Juglandaceae family. The fruit includes four main parts: the kernel, the skin, the shell, and the green husk. It is widely cultivated due to its edible kernel. In walnut production centers, high amounts of the husk as an agro-forest waste product are produced and discarded away. Recently, it has been demonstrated that the walnut green husk could be valued as a source of different natural bioactive compounds with excellent antioxidant and antimicrobial properties. Regarding this respect, in this contribution, the current scientific knowledge on the antioxidant and antiradical activities, various identified and isolated individual chemical constituents, as well as the functional applications of the walnut husk with more emphasis on the Persian walnut (Juglans regia L.) are reviewed.

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Section: The Health Benefits Of Walnutsmentioning

confidence: 99%

Section: Antioxidant Content and Radical Scavenging Activity Of Wamentioning

confidence: 99%

A Comprehensive Review on the Chemical Constituents and Functional Uses of Walnut (Juglans spp.) Husk

Jahanban-Esfahlan

Ostadrahimi

Tabibiazar

et al. 2019

IJMS

146

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“…Almond hulls are rich source of triterpenoids (betulinic, urosolic, and oleanolic acids) flavonol glycosides, phenolic acids, catechin, protocatechuic acid, vanillic acid, and other polyphenolioc compounds; therefore, this byproduct may be an interesting source of natural antioxidants and other bioactive compounds [4][5][6]. Moreover, the extraction of these products from almond residues could contribute to a reduction in the environmental impact and provide added value to the overall almond production.…”

Section: Introductionmentioning

confidence: 99%

Characterization of Polyphenolic Compounds Extracted from Different Varieties of Almond Hulls (Prunus dulcis L.)

et al. 2019

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Ultrasound-assisted extraction (UAE) was applied as a pretreatment technique to improve the recovery of polyphenols from the almond hulls of four Tunisian and three Italian almond varieties, followed by the characterization with HPLC-DAD. The operating parameters (solid/liquid ratio, extraction time, and ethanol concentrations) were optimized using a Response Surface Methodology. A polynomial equation was calculated to describe the relationship between the operating parameters and dependent variables as total polyphenolic content (TPC) and antioxidant activity (RSA). A desirability function approach was used to determine the optimum conditions for operating parameters: a solid:solvent ratio of 2 g/100 mL, an extraction time of 13 min, and an ethanol concentration of 51.2%. Among the almond varieties, Pizzuta and Fakhfekh showed the highest polyphenol content and antioxidant activity. HPLC-DAD analysis of almond hull extracts confirmed that chlorogenic acid, catechin, and protocatechuic acid were the most important polyphenols in almond hull. The results highlighted that UAE could be an effective technique for the recovery of phenolic compounds from almond hull, thereby making this byproduct a promising source of compounds with potential applications in food and healthcare sectors.

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“…Previous investigations on P. dulcis husks showed interesting antioxidant and antiradical properties . Moreover, almond husks have been tested on hyperlipidemic rats to test their antioxidant properties on plasma and liver, showing promising results …”

Section: Introductionmentioning

confidence: 99%

HR‐LC‐ESI‐Orbitrap‐MS based metabolite profiling of Prunus dulcis Mill. (Italian cultivars Toritto and Avola) husks and evaluation of antioxidant activity

Bottone

Masullo

Montoro

et al. 2019

Phytochemical Analysis

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Introduction Prunus dulcis Mill. is a plant cultivated for the production of its edible seeds, known as sweet almonds. In the last decades almond demand has highly increased due to their wide use in the industrial manufacturing of almond‐based foods; this has led to a huge production of waste materials, mainly corresponding to shells and husks. Objective To achieve a deeper understanding of the chemical composition of almond husks with the aim of exploring these byproducts as a source of bioactives to be used in nutraceutical and cosmetic formulations. Methods Methanol, ethanol and ethanol–water extracts of the almond husks were analysed by high‐resolution liquid chromatography electrospray ionisation Orbitrap mass spectrometry (HR‐LC‐ESI‐Orbitrap‐MS) in negative ion mode. Tandem mass spectrometry (MS/MS) data were acquired by using the Data‐Dependent Scan experiment, allowing the precursor ion to be selected as the most intense peak during LC‐MS analyses. Nuclear magnetic resonance (NMR) experiments were performed on a Bruker DRX‐600 spectrometer. Folin–Ciocalteu, DPPH• (2,2‐diphenyl‐1‐picrylhydrazyl) and TEAC (Trolox equivalent antioxidant capacity) assays were employed to determine the total phenolic content and the radical scavenging activity of the extracts. Results The LC‐MS/MS analysis of the methanol extract guided the isolation of phloroglucinol derivatives, flavonoids and terpenes. Eco‐friendly extraction methods showed to be selective in extracting flavonoids while the comparison of the LC‐MS profiles of the Italian cultivars Toritto and Avola showed significant differences, confirming how different growing conditions may influence the metabolome of a plant species. Conclusion This study led to a deeper insight into the chemical constituents of almond husks and showed how the eco‐friendly extraction resulted in an effective method to obtain extracts rich in antioxidant sources.

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The beneficial effects of almond (Prunus amygdalus Batsch) hull on serum lipid profile and antioxidant capacity in male rats

Cited by 14 publications

References 49 publications

A Comprehensive Review on the Chemical Constituents and Functional Uses of Walnut (Juglans spp.) Husk

A Comprehensive Review on the Chemical Constituents and Functional Uses of Walnut (Juglans spp.) Husk

Characterization of Polyphenolic Compounds Extracted from Different Varieties of Almond Hulls (Prunus dulcis L.)

HR‐LC‐ESI‐Orbitrap‐MS based metabolite profiling of Prunus dulcis Mill. (Italian cultivars Toritto and Avola) husks and evaluation of antioxidant activity

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