The behavioural, cardiovascular and respiratory actions of morphine-N-oxide in the dog

Fennessy, M. R.

doi:10.1016/0014-2999(69)90034-x

Cited by 4 publications

(1 citation statement)

References 8 publications

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“…Although IP injection of morphine in fish induced tachypnea immediately, respiratory rate quickly returned to baseline level and did not change significantly during the next 72 hours. The lack of a long-term effect of morphine on the respiratory rate of flounder is in contrast to the respiratory depression detected in some mammals (eg, dogs 18 ) following morphine administration.…”

Section: Discussionmentioning

confidence: 56%

Cardiorespiratory effects and efficacy of morphine sulfate in winter flounder (Pseudopleuronectes americanus)

Newby

Gamperl²,

Stevens³

2007

ajvr

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Section: Discussionmentioning

confidence: 56%

Cardiorespiratory effects and efficacy of morphine sulfate in winter flounder (Pseudopleuronectes americanus)

Newby

Gamperl²,

Stevens³

2007

ajvr

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Die chronotrope Wirkung der Urethan-Narkose auf das M�useherz

Lehr

Haeser

Werner

1972

Naunyn-Schmiedeberg's Arch. Pharmacol.

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Reversal by acupuncture of cardiovascular depression induced with morphine during halothane anaesthesia in dogs

Lee

Clifford

Lee

et al. 1981

Canad. Anaesth. Soc. J.

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The cardiovascular effects of morphine sulphate and/or acupuncture by means of electrocautery at Jen Chung (Go-26) were studied in 35 dogs. All animals were maintained under anaesthesia with halothane 0.75 per cent supplemented by the intravenous administration of suceinylcholine to allow controlled ventilation during a two hour period of monitoring. Cardiac output, stroke volume, heart rate, mean arterial pressure, pulse pressure, central venous pressure, total peripheral resistance, [H +] (pH) Pat02, Pa02 and base deficit were measured in each dog.Morphine 0.5 rag. kg -~, administered alone as a single bolus, significantly (P < 0.05) decreased cardiac output, heart rate, mean arterial pressure, and significantly increased stroke volume and pulse pressure in dogs under halothane anaesthesia. Acupuncture by electrocautery alone induced a significant increase in cardiac output, stroke volume, heart rate, mean arterial pressure and pulse pressure with a significant decrease in total peripheral resistance following halothane. Acupuncture at Jen Chung (Go-26) for 10 minutes following the intravenous administration of morphine caused a significant increase in cardiac output, heart rate and mean arterial pressure with a significant decrease in central venous pressure and total peripheral resistance during halothane anaesthesia.The depressant effect of morphine on cardiac output, heart rate and mean arterial pressure in dogs under halothane anaesthesia appears to be reversed by acupuncture by electrocautery at Jen Chang (Go-26). Stimulation of this acupuncture locus could be helpful in resuscitating patients whose cardiovascular system is depressed by morphine and/or halothane anaesthesia.KEY WORDS: ACUPUNCTURE, Reversal of cardiovascular depression.

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The behavioural, cardiovascular and respiratory actions of morphine-N-oxide in the dog

Cited by 4 publications

References 8 publications

Cardiorespiratory effects and efficacy of morphine sulfate in winter flounder (Pseudopleuronectes americanus)

Cardiorespiratory effects and efficacy of morphine sulfate in winter flounder (Pseudopleuronectes americanus)

Die chronotrope Wirkung der Urethan-Narkose auf das M�useherz

Reversal by acupuncture of cardiovascular depression induced with morphine during halothane anaesthesia in dogs

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