The barrel-shaped cervical carcinoma

Lu, Tao; Macasaet, Milagros A.; Nelson, James H.

doi:10.1016/0002-9378(76)90060-0

Cited by 8 publications

(3 citation statements)

References 10 publications

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“…In the foregoing review, survival was correlated with the stage as well as the lesion size. Correlation of in-creasing cervical tumor volume with worsening survival has also been emphasized by other studies [1,10,14]. Since there is a rapid decrease in the dose delivered with distance from the sources used in intracavitary treatment, large tumor volumes may extend beyond the high-dose region.…”

Section: Discussionmentioning

confidence: 99%

“…Twenty-three patients received radiation therapy after an initial radical hysterectomy for close or positive margins (9) and positive pelvic nodes (14). Seventeen patients underwent a simple hysterectomy and seven a radical hysterectomy after radiation, usually for bulky lesions.…”

Section: Methodsmentioning

confidence: 99%

“…Patients with stage IB lesions were treated in a variety of manners including radical hysterectomy with postoperative radiation, radiation only, or hysterectomy after radiation. Twenty-three patients received radiation therapy after an initial radical hysterectomy for close or positive margins (9) and positive pelvic nodes (14). Seventeen patients underwent a simple hysterectomy and seven a radical hysterectomy after radiation, usually for bulky lesions.…”

Section: Methodsmentioning

confidence: 99%

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Radiation therapy in the treatment of cervical Cancer: The university of Chicago/Michael reese hospital experience

Rader

Haraf

Halpern

et al. 1990

Journal of Surgical Oncology

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A retrospective analysis was conducted on 307 patients referred for radiation therapy at The University of Chicago and Michael Reese Hospital between 1971 and 1986. Median follow-up was 6.4 years. Treatment techniques varied during the time of the study. Actuarial disease-free survivals were 78%, 64%, 55%, 33%, 41%, and 60% for stage IB, IIA, IIB, IIIA, IIIB, and IVA, respectively. Stage, size of the cervical lesion, and hemoglobin level during treatment were prognostic factors. Treatment technique as well as time dose factors were analyzed with respect to survival, failures, and complications.

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Section: Discussionmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

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Radiation therapy in the treatment of cervical Cancer: The university of Chicago/Michael reese hospital experience

Rader

Haraf

Halpern

et al. 1990

Journal of Surgical Oncology

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Combined radiation therapy and extrafascial hysterectomy in the treatment of stage IB barrel-shaped cervical cancer

Gallion

Nagell

Donaldson

et al. 1985

Cancer

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Seventy-five patients with bulky barrel-shaped Stage IB cervical cancers, treated at the University of Kentucky from 1965 to 1981, were the subjects of this investigation. Thirty-two of these patients were treated with radiation therapy alone and 43 were treated with radiation followed by extra-fascial hysterectomy. There were no significant differences in age, gravidity, or tumor cell type between the two treatment groups. Patients were seen at regular intervals from 2 to 11 years after treatment and none were lost to follow-up. Recurrent cancer was noted in 47% of patients treated by radiation alone as compared to 16% of those treated with combined therapy (P less than 0.01). The incidence of pelvic recurrence was reduced from 19% to 2% and extrapelvic recurrence from 16% to 7% in patients treated by combination therapy. No rectal or urinary tract fistulae were noted after extra-fascial hysterectomy. The findings of this study suggest that the use of extra-fascial hysterectomy following radiation therapy in patients with bulky Stage IB cervical cancer causes a significant reduction in tumor recurrence without producing an increase in treatment-related complications.

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Treatment of locally advanced cancer of the cervix with interstitial parametrial implants

Aristizabal¹

1987

Cancer Treatment and Research

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The barrel-shaped cervical carcinoma

Cited by 8 publications

References 10 publications

Radiation therapy in the treatment of cervical Cancer: The university of Chicago/Michael reese hospital experience

Radiation therapy in the treatment of cervical Cancer: The university of Chicago/Michael reese hospital experience

Combined radiation therapy and extrafascial hysterectomy in the treatment of stage IB barrel-shaped cervical cancer

Treatment of locally advanced cancer of the cervix with interstitial parametrial implants

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