The Bangladesh Risk of Acute Vascular Events (BRAVE) Study: objectives and design

Chowdhury, Rajiv; Alam, Dewan S.; Fakir, Ismail Ibrahim; Adnan, Sheikh Daud; Naheed, Aliya; Tasmin, Ishrat; Monower, Mostafa; Hossain, Ferdous; Hossain, Fatema Mahjabin; Rahman, Mostafizur; Afrin, Sadia; Roy, Anjan Kumar; Akter, Minara; Sume, Sima Akter; Biswas, Ajoy Kumer; Pennells, Lisa; Surendran, Praveen; Young, Robin; Spackman, Sarah; Hasan, Khaled; Harshfield, Eric L.; Sheikh, Nasir; Houghton, Richard; Saleheen, Danish; Howson, Joanna M.M.; Butterworth, Adam S.; Raqib, Rubhana; Majumder, Abdulla Al Shafi; Danesh, John; Angelantonio, Emanuele Di

doi:10.1007/s10654-015-0037-2

Cited by 32 publications

(26 citation statements)

References 27 publications

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“…who found the maximum number of patients in this similar age group. The mean age in this present study was 53.38 ± 10.22 years, which is comparable with the studies of Patil, B.M.,5 &Chowdhury et al,6 who found mean age of the patients 53.61 ± 12.43 years & 53 ± 10 years respectively.…”

supporting

confidence: 91%

The Pattern of Cardiac Arrhythmias in Acute ST Elevated Myocardial Infarction and their in-hospital Outcome

et al. 2020

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Background: Acute myocardial infarction (AMI) is a major cause of death worldwide with arrhythmia being the most common determinant in the post-infarction period. Identification and management of arrhythmias at an early period of acute MI has both short term and long term significance. Objective: The aim of the study is to evaluate the pattern of arrhythmias in acute STEMI in the first 48 hours of hospitalization and their inhospital outcome. Methods: A total of 50 patients with acute STEMI were included in the study after considering the inclusion and exclusion criteria. The patients were observed for the first 48 hours of hospitalization for detection of arrhythmia with baseline ECG at admission and continuous cardiac monitoring in the CCU. The pattern of the arrhythmias during this period & their in-hospital outcome were recorded in predesigned structured data collection sheet. Result: The mean age was 53.38 ± 10.22 years ranging from 29 to 70 years. Most of the patients were male 42(84%). Majority of the patients had anterior wall ( anterior, antero-septal & extensive anterior) myocardial infarction (54%). Sinus tachycardia in isolation was the most common arrhythmia observed in 36.8% of patients followed by sinus bradycardia (22.8%), ventricular tachycardia (19.3%), ventricular ectopic (12.3%),first degree AV block (5.3%), complete heart block and atrial ectopic 1.7% each. Tachyarrhythmias were more common in anterior wall myocardial infarction, whereas bradyarrhythmias were more common in inferior wall myocardial infarction. Among studied patients, 72% had favourable outcome , followed by acute left ventricular failure 10%, cardiogenic shock & lengthening of hospital stay 8% each and death 2%. Conclusion: The commonest arrhythmias encountered were sinus tachycardia followed by sinus bradycardia, ventricular tachycardia, ventricular ectopic, AV block and atrial ectopic. The incidence of mortality was 2%. University Heart Journal Vol. 16, No. 1, Jan 2020; 16-21

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confidence: 91%

The Pattern of Cardiac Arrhythmias in Acute ST Elevated Myocardial Infarction and their in-hospital Outcome

et al. 2020

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“…17 In concert with this concept, the initial analyses of the ongoing Bangladesh Risk of Acute Vascular Events (BRAVE) study indicates that Bangladeshis are genetically distinct from major non-South Asian ethnicities, as well as distinct from other South Asian ethnicities and were perhaps genetically closest to (though still distinct from) Sri Lankan Tamils. 64 There may also be genetic susceptibility to hypertension. The association between angiotensin converting enzyme (ACE) gene polymorphism and blood pressure has been studied inadequately in Bangladeshi population.…”

Section: Ethnicity and Geneticsmentioning

confidence: 99%

Cardiovascular Disease in Bangladesh: A Review

2017

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Abstract:Like elsewhere, cardiovascular disease (CVD) is an increasingly important cause of morbidity and mortality in Bangladesh. Over the past few decades, because of epidemiological transition, the prevailing disease pattern in this country changed from predominantly communicable to predominantly non-communicable disease, CVD contributes to the latter a lot. Actually, CVD particularly coronary artery disease (CAD) is getting epidemic proportion day by day. Hypertension and heart failure are on the rise, whereas the prevalence of acute rheumatic fever is declining. However, despite some efforts, reliable data concerning various aspects of CVD is inadequate at present. The current prevalence of hypertension, CAD, rheumatic fever and rheumatic heart disease and stroke may be 20-25%, 4-6%, <1/1000, 0.3-1.0% respectively. Besides conventional risk factors for different CVD, genetic predisposition and some novel issues like high salt intake, arsenicosis, hypovitaminosis D and air pollution may play important role in the aetiopathogenesis of CVD in this population. Formulation of appropriate policy and more emphasis on preventive strategy may help combat CVD in Bangladesh.

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“…19 The high rate of smoking (79%) was also evident in the BRAVE study conducted in National Institute of Cardiovascular Diseases among patients with ischaemic heart disease. 20 About one third of the patients were diabetic. The prevalence of DM was maximum in the age group of 60-69 years.…”

Section: Resultsmentioning

confidence: 99%

Modifiable Cardiovascular Risk Factors in Hypertensive Patients

Ullah¹,

Saha²

2018

Cardiovasc. j.

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Background: Hypertension is one of the most important noncommunicable diseases. Presence of other cardiovascular risk factors in hypertensive patients increases the risk of ischaemic heart disease and cerebrovascular diseases. We evaluated the prevalence of cardiovascular risk factors among the hypertensive patients.Methods: Patients presenting to the outpatient department of a secondary hospital were included in the study. The prevalence of diabetes mellitus, current smoking, family history of ishaemic heart disease, dyslipidaemia and nephropathy were evaluated.Results: A total of 144 patients were included in the study (male 66 & female 78). 29.8% patients were smoker (57% of male patients and 6% of female patients); 34% patients were diabetic; 27% patients had raised total cholesterol, 40.3% had reduced HDL, 22% had raised LDL, 36.8% had raised triglyceride and 33.3% patients had nephropathy (proteinuria/ raised serum creatinine).Conclusion: The prevalence of cardiovascular risk factors, specifically smoking, diabetes mellitus, raised LDL and nephropathy were more among the hypertensive patients. All the hypertensive patients should be evaluated for modifiable cardiovascular risk factors during diagnosis and follow up. Treatment of these risk factors can improve the prognosis of the hypertensive patients.Cardiovasc. j. 2018; 11(1): 10-16

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The Bangladesh Risk of Acute Vascular Events (BRAVE) Study: objectives and design

Cited by 32 publications

References 27 publications

The Pattern of Cardiac Arrhythmias in Acute ST Elevated Myocardial Infarction and their in-hospital Outcome

The Pattern of Cardiac Arrhythmias in Acute ST Elevated Myocardial Infarction and their in-hospital Outcome

Cardiovascular Disease in Bangladesh: A Review

Modifiable Cardiovascular Risk Factors in Hypertensive Patients

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