The balance between helper T 17 and regulatory T cells in osteoimmunology and relevant research progress on bone tissue engineering
Shuyu Zhu,
Jing Zhou,
Zhigang Xie
Abstract:BackgroundBone regeneration is a well‐regulated dynamic process, of which the prominent role of the immune system on bone homeostasis is more and more revealed by recent research. Before fully activation of the bone remodeling cells, the immune system needs to clean up the microenvironment in facilitating the bone repair initiation. Furthermore, this microenvironment must be maintained properly by various mechanisms over the entire bone regeneration process.ObjectiveThis review aims to summarize the role of th… Show more
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