1963
DOI: 10.1001/archderm.1963.01590240153025
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The Bacteriology of Acne

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Cited by 61 publications
(22 citation statements)
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“…The resulting skin condition with sebum enrichment is prone to the anaerobic growth of Propionibacterium acnes, which is the main causative microorganism in acne. In addition, Staphylococcus epidermidis and Pitryosporum ovale are present in acne lesions [6]. Proliferation of these microorganisms, mainly P. acnes, leads to inflammatory lesions and severe acne.…”
Section: Introductionmentioning
confidence: 99%
“…The resulting skin condition with sebum enrichment is prone to the anaerobic growth of Propionibacterium acnes, which is the main causative microorganism in acne. In addition, Staphylococcus epidermidis and Pitryosporum ovale are present in acne lesions [6]. Proliferation of these microorganisms, mainly P. acnes, leads to inflammatory lesions and severe acne.…”
Section: Introductionmentioning
confidence: 99%
“…Propionibacterium acnes can regularly be isolated from acne vulgaris lesions (14) and frequently from actinomycotic (9) or nonspecific anaerobic infectious processes (13). There seems to be strong evidence that P. acnes is an important etiological factor in acne vulgaris because of the release of large amounts of free fatty acids from sebum triglycerides (16).…”
mentioning
confidence: 99%
“…It can be concluded that erythro mycin probably acts by suppressing the bacterial population in the sebaceous glands. Three groups of microorganisms, C. acnes, S. epidermidis and Pityrosporum are generally found in the comedones [II, 23,32], We are therefore now studying both in vitro and in vivo the effect of erythromycin stearate on bacterial flora, subcultured under standardised conditions on special media. The results of the running quantitative cultures before and after erythromycin therapy (250 mg daily for 1-3 weeks) show that erythromycin only slightly reduces the C. acnes counts.…”
Section: Discussionmentioning
confidence: 99%