Abstract:Objectibe The rate of pancreatic cell regeneration after avocado leaf extract intervention in a diabetic animal model induced by streptozotocin was investigated in this study. Method: Experimental study was conducted on 18 male white rats as subjects, which were divided into 6 groups, 3 animals of each. Those were G1 (Feed + Streptozotocin + 10% Sucrose + 100 mg/kg b.w. of extract + 0.5% NaCMC), G2 (Feed + Streptozotocin + 10% Sucrose + 150 mg/kg b.w. of extract + 0.5% NaCMC), G3 (Feed + Streptozotocin + 10% S… Show more
“…Increasing the dose of avocado extract seems to increase the regenerative effect on the pancreas. However, the most severe cell damage was seen in the group that received 0.5% Na-CMC vehicle (Rahman et al, 2021). This suggests that avocado ethanolic extract can enhance pancreatic cell regeneration and be a potential candidate as a regenerative agent in conditions of pancreatic cell damage.…”
Section: Avocado Fruit Peel Extract and Antidiabeticmentioning
confidence: 93%
“…Follow-up research conducted by Rahman et al (2020) showed that avocado leaf extract has the potential to increase kidney cell regeneration in male white rats with diabetes (Rahman et al, 2022). The results showed that the dose of avocado leaf extract affected the level of kidney damage, where the higher the dose of the extract given, the lower the level of kidney damage that occurred.…”
Section: Avocado Fruit Peel Extract and Antidiabeticmentioning
This literature review aimed to determine the effect of giving avocado leaf extract and seeds as an antidiabetic. The literature study was conducted by choosing an experimental research design using experimental animal subjects. The results of a review of 9 articles showed that avocado seed and leaf extract as antidiabetics were that both of them showed potential as promising antidiabetic agents. Research on avocado seed extract showed that administration of avocado seed extract positively improved glycemic control and reduced diabetes symptoms in diabetic rats. On the other hand, research on avocado leaf extract showed that administration of avocado leaf extract could also reduce blood glucose levels and regulate lipid profiles in diabetic rats. These two extracts show different but consistent effects in improving blood glucose regulation and lipid profiles in diabetic conditions. Avocado seed extract showed a more significant effect in reducing diabetes symptoms, while avocado leaf extract showed promising potential in regulating blood glucose levels and lipid profiles.
“…Increasing the dose of avocado extract seems to increase the regenerative effect on the pancreas. However, the most severe cell damage was seen in the group that received 0.5% Na-CMC vehicle (Rahman et al, 2021). This suggests that avocado ethanolic extract can enhance pancreatic cell regeneration and be a potential candidate as a regenerative agent in conditions of pancreatic cell damage.…”
Section: Avocado Fruit Peel Extract and Antidiabeticmentioning
confidence: 93%
“…Follow-up research conducted by Rahman et al (2020) showed that avocado leaf extract has the potential to increase kidney cell regeneration in male white rats with diabetes (Rahman et al, 2022). The results showed that the dose of avocado leaf extract affected the level of kidney damage, where the higher the dose of the extract given, the lower the level of kidney damage that occurred.…”
Section: Avocado Fruit Peel Extract and Antidiabeticmentioning
This literature review aimed to determine the effect of giving avocado leaf extract and seeds as an antidiabetic. The literature study was conducted by choosing an experimental research design using experimental animal subjects. The results of a review of 9 articles showed that avocado seed and leaf extract as antidiabetics were that both of them showed potential as promising antidiabetic agents. Research on avocado seed extract showed that administration of avocado seed extract positively improved glycemic control and reduced diabetes symptoms in diabetic rats. On the other hand, research on avocado leaf extract showed that administration of avocado leaf extract could also reduce blood glucose levels and regulate lipid profiles in diabetic rats. These two extracts show different but consistent effects in improving blood glucose regulation and lipid profiles in diabetic conditions. Avocado seed extract showed a more significant effect in reducing diabetes symptoms, while avocado leaf extract showed promising potential in regulating blood glucose levels and lipid profiles.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.