We predict the production yield of a medical radioisotope 67 Cu using 67 Zn(n, p) 67 Cu and 68 Zn(n, pn) 67 Cu reactions with fast neutrons provided from laser-driven neutron sources (LDNSs).The neutrons were generated by the p+ 9 Be and d+ 9 Be reactions with high energy ions accelerated by laser-plasma interaction. We evaluated the yield to be (3.3±0.5)×10 5 atoms for 67 Cu, corresponding to a radioactivity of 1.0±0.2 Bq, for a Zn foil sample with a single laser shot. Using a simulation with this result, we estimated 67 Cu production with a high-frequency laser. The result suggests that it is possible to generate 67 Cu with a radioactivity of 270 MBq using a future laser system with a frequency of 10 Hz and 10000-s radiation in a hospital.