The autistic brain can process local but not global emotion regularities in facial and musical sequences

Xu, Jie; Zhou, Linshu; Liu, Fang; Xue, Chao; Jiang, Jun; Jiang, Cunmei

doi:10.1002/aur.2635

Cited by 5 publications

(6 citation statements)

References 137 publications

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“…Similarly, in depressed patients show reduced P300 to local oddballs before antidepressant treatment compared to healthy control group. Interestingly, after medication treatment, the depressed group recovered the P300 response to similar levels as in healthy controls 104 . These results suggest that as patients improve clinically, they may be retuning their predictive capabilities.…”

Section: Clinical Populationsmentioning

confidence: 64%

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Predictive Coding: A more cognitive process than we thought?

Gabhart,

Xiong,

Bastos

2023

Preprint

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The brain is thought to generate internal predictions. The local-global oddball paradigm has been used to investigate predictive coding. Local oddballs are created by stimulus repetition and can be explained by release from adaptation. Global oddballs are created by higher-order patterns that cannot be explained by low-level mechanisms. Initial neuroimaging experiments revealed local/global oddball activation of sensory and higher-order networks. Recent studies of spiking in sensory areas show no response to global oddballs – a challenge to predictive coding. We propose a conceptual framework, predictive routing. In predictive routing, not all feedforward sensory responses are prediction errors. Instead, alpha/beta oscillations provide predictive suppression at the appropriate level of processing. We apply this model to autism spectrum disorder (ASD) and schizophrenia (ScZ).

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Section: Clinical Populationsmentioning

confidence: 64%

“…In addition, ScZ exhibits a reduction of MMN responses to local oddballs [101][102][103] . An ASD study showed no responses to global oddball processing; however, there was enhanced local oddball visual processing 104 .…”

Section: Clinical Populationsmentioning

confidence: 95%

Predictive Coding: A more cognitive process than we thought?

Gabhart,

Xiong,

Bastos

2023

Preprint

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“…These findings suggest that there may be abnormalities in global prediction within the ASD population. In addition, individuals with ASD demonstrated MMN in response to violations of local emotion regularity for both faces and music, but their responses to global emotion regularity violations were absent [49]. These results, derived from a group level analysis, suggest a potential deficiency in global prediction within ASD.…”

Section: Discussionmentioning

confidence: 99%

Diverse Configurations of Erroneous Predictive Coding Across Brain Hierarchies in a Non-Human Primate Model of Autism Spectrum Disorder

Chao,

Komatsu,

Matsumoto

et al. 2023

Preprint

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In autism spectrum disorder (ASD), atypical sensory experiences are often associated with irregularities in predictive coding, which proposes that the brain creates hierarchical sensory models via a bidirectional process of predictions and prediction errors. However, it remains unclear how these irregularities manifest across different functional hierarchies in the brain. To address this, we used high-density electrocorticography (ECoG) in a non-human primate model of ASD during an auditory task with two layers of temporal control, and applied a quantitative model to quantify the integrity of predictive coding across two distinct hierarchies. Our results demonstrate that ASD is characterized by sensory hypersensitivity and unstable predictions across two brain hierarchies, and reveal the associated spatio-spectro-temporal neural signatures. Importantly, we observe diverse configurations of underestimation or overestimation of sensory regularities within these hierarchies. This work provides a multi-layered biomarker for ASD, contributing to our understanding of its diverse symptoms.

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“…Some researchers have argued that these people actually confuse their emotional experience with the emotions expressed by the music [6]. Emotions are closely related to human needs, and because music itself cannot satisfy the goals or desires of reallife listeners, it cannot evoke "real" tangible feelings such as "sadness" [7][8][9].…”

Section: Introductionmentioning

confidence: 99%

Musical Melody and Emotional Evocation - An Empirical Study from Statistical Analysis

2024

Applied Mathematics and Nonlinear Sciences

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Music is a product of human conscious activity, which, as a special form of artistic expression, can directly hit the psyche and trigger people’s strong emotional experiences. In this study, the continuity of pitch significance is first utilized to represent the musical melody and the feature extraction of polyphonic musical melody is carried out based on harmonic peak and harmonic sum functions. Based on this basis, the features of the extracted musical melody are recognized by combining convolutional neural networks. In addition, the study also constructs an emotion evocation model based on musical melody, and empirically demonstrates the relationship between musical melody and emotion evocation using statistical analysis. The p-values of different music melodies and different music preferences are all less than 0.05. According to the difference analysis, sad emotions have an arousal rate of 90%, which makes them the easiest to induce and arouse. The p-value for the three factors between musical melody, gender, and professional background was less than 0.05, and the interaction was significant. Music melody, gender, and professional background of emotion evocation have a considerable difference. The influence of emotion evocation has a significant effect. While the role of music preferences on emotion evocation is not substantial, the trend and characteristics of different music melody types evoked emotions provide an effective and realistic basis.

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The autistic brain can process local but not global emotion regularities in facial and musical sequences

Cited by 5 publications

References 137 publications

Predictive Coding: A more cognitive process than we thought?

Predictive Coding: A more cognitive process than we thought?

Diverse Configurations of Erroneous Predictive Coding Across Brain Hierarchies in a Non-Human Primate Model of Autism Spectrum Disorder

Musical Melody and Emotional Evocation - An Empirical Study from Statistical Analysis

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