The Athlete’s Heart

Pluim, Babette M; Zwinderman, A. H.; Laarse, A. van der; Wall, Ernst E. van der

doi:10.1161/01.cir.101.3.336

Cited by 835 publications

(317 citation statements)

References 78 publications

Supporting

Mentioning

277

Contrasting

Unclassified

Order By: Relevance

“…The LV responds by increasing its internal diameter. 23,24 Therefore, the aerobic-trained heart develops eccentric hypertrophy. 25 The results of the present study show that in rats submitted to endurance training, the diameter of the axon and of the myelin sheath of the vagus nerve fibers increases.…”

Section: Discussionmentioning

confidence: 99%

Endurance training induces structural and morphoquantitative changes in rat vagus nerve

Pianca

Neto

Pithon‐Curi

et al. 2015

Rev Bras Med Esporte

View full text Add to dashboard Cite

Introduction: Many nervous system tissues and cells suffers positive changes when faced to exercise training. However, data on vagus nerve adaptation from exercise-induced study is absent. Objective: To analyze the effect of an endurance training on the vagus nerve morphology of rats. Methods: Wistar rats (6 months of age) were divided into two groups: control group (CG, n=8), and aerobic trained group (AT, n=8). AT was submitted to a treadmill training program of five times per week during 12 weeks. The maximum speed stipulated in the training protocol corresponded to 60% of the mean maximum intensity achieved by the group in the test of maximum effort. Results: Twelve weeks of treadmill training resulted in left ventricular hypertrophy in the AT group compared to CG. There was a significant increase in the area of both the myelinated and unmyelinated axons, and in the area of myelin sheath with training. The number of neurotubules and neurofilaments in myelinated fibers of aerobic trained group was significantly greater than CG (p≤0.05). Conclusion: Endurance training promoted significant increase in morphometric parameters of the vagus nerve in the same way it affect somatic nerves.

show abstract

Section: Discussionmentioning

confidence: 99%

Endurance training induces structural and morphoquantitative changes in rat vagus nerve

Pianca

Neto

Pithon‐Curi

et al. 2015

Rev Bras Med Esporte

View full text Add to dashboard Cite

show abstract

“…LVM is affected by many factors including age, gender, body size and composition, 6,7 athletic training, 38 blood pressure 39,40 and systemic disease processes such as diabetes. 41 To account for the influence of body composition on LVM, various estimates of body size have been used to normalise LVM, including dividing mass by BSA 42 or by height 2.7 (ref.…”

Section: Discussionmentioning

confidence: 99%

Geographic variation in left ventricular mass and mass index: a systematic review

et al. 2011

View full text Add to dashboard Cite

Left ventricular (LV) hypertrophy, defined as an abnormal increase in LV mass (LVM), is an important prognostic indicator and therapeutic target. LVM is often divided by body surface area to derive indexed mass; however, this does not correctly identify pathological LV hypertrophy in all people, especially when body composition is altered, or in different ethnic groups. We evaluated published ranges of echocardiographic LVM in healthy adult populations from different countries, excluding control groups, and compared them with the American Society of Echocardiography reference ranges. A total of 33 studies met the inclusion criteria. In men and women, there was wide variation in the ranges of LVM with a tendency for the upper limit to increase geographically westward; this variation remained for indexed mass. Several ranges fell outside the upper reference limits: in men, 13 of the mass ranges and 16 of indexed mass; and in women, 8 mass and 16 indexed mass. This review has shown that current guidelines may need revision as some published series suggest that greater LV mass should be considered normal. This may be explained by ethnic differences and supports the need for widely applicable and ethnically diverse reference ranges to be established.

show abstract

“…9 LV geometry among athletes is sport specific. [10][11][12] Individuals who participate in sports with significant isotonic physiology tend to develop eccentric left ventricular remodeling which is characterized by balanced chamber dilation and wall thickening. In contrast, athletes participating in sports with predominant isometric physiology most commonly develop concentrate left ventricular remodeling which is characterized by wall thickening in the absence of chamber dilation.…”

Section: Myocardial Adaptations To Exercisementioning

confidence: 99%