The associations of TMJ pain and bone characteristics on the activities of daily living

Abstract

The aim of this investigation was to analyze the associations of TMJ pain/discomfort and bone characteristics on the activities of daily living in a population based study. Methods: The study included 95 randomly selected participants. The impact of temporomandibular joint pain/discomfort on the daily activeties was assessed by using the daily living scale by List and Helkimo (1995). The levels of serum type I collagen telopeptide fragments (P1NP), C-telopeptide crosslaps of type I collagen (CTX-1), and vitamin D (25 (OH) D) were analysed. The Mann-Whitney U-test, Spearman rank correlation coefficent (rs) were used for statistical analyses. Results: Activities of daily living were influenced by temporomandibular joint pain/discomfort to varying degrees. The degree of pain/discomfort during eating was correlated with the level of C-telopeptide crosslaps of type I collagen (p = 0.02) and type 1 collagen telopeptide fragments (p = 0.04). The females in the study had significantly lower vitamin D levels compared to males (p = 0.04). Conclusions: This population based study indicates that TMJ pain/discomfort exerts a significant negative influence on activities of daily living and is related to the biochemical markers of bone turnover and 25 (OH) D level. Several functions of daily activities such as social life, exercising and eating are the most disturbed

Importance of Bone Markers and Radiological Status on Clinical Signs of Temporomandibular Joint Disorders

“…In chronic pain, psychological factors may become more obvious and prominent [17]. In a population-based study, 47% subjects had TMJ problems where pain is commonly accompanied by stiffness, sounds and functional limitations, which result in a decreased quality of life, and thus exert a significant negative impact on activities of daily living (ADL) [5]. The following everyday activities such as eating, talking, yawning and laughing were more disturbed [18,19,20].…”

“…Only a few systematic reviews have addressed to daily activities or quality of life in relation to management of TMJ disorders. It is concluded that the use of specific questionnaires is justified for assessment of the character of TMJ pain [5].…”

“…Limited clinical research has focused on the specific effects of vitamin D deficiency on jaw pain. It is reported that vitamin D deficiency can cause predisposition to TMJ disorders [5,77,107,108].…”

“…It was found [5] that lowering of 25(OH)D correlated negatively with activities of daily living such as social life with family (ADL 1), other social activities (ADL 4), exercising (ADL 5), performing hobbies (ADL 6), concentrating (ADL 8), eating (ADL 9), how much the pain/ discomfort affects daily activities (ADL 12; Fig. 6).…”

“…Many researches focus on the role of biochemical mediators in development and progression of TMJ pain and dysfunction. There has been found association between bone markers (procollagen type I N-terminalpropeptide (P1NP), C-telopeptide crosslaps of type I collagen (CTX-1) as well as vitamin D (25(OH)D) and TMD [3,4,5]. Several biochemical markers of bone turnover can be used to predict individual bone loss on risk for TMJ pathologies [6].…”