The associations between anxiety/depression and plasma chromogranin A among healthy workers: Results from EHOP study

Abstract

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Associations between chronic work stress and plasma chromogranin A/catestatin among healthy workers

“…All the subjects came from the Emotion and Health among Occupational Population (EHOP) study which was a registry study to explore the associations between emotional factors and physical health among Chinese occupational population. 29 There were 300 workers anticipated this study when they underwent physical checkups at the Peking University Third Hospital in August 2016. The 32 participants who had a history of chronic diseases or had abnormal results of this physical checkup, such as cardiovascular disease, cerebrovascular disease, hypertension, hyperlipidemia, diabetes mellitus, or immunological disease were excluded, and 8 participants with incomplete questionnaires were also excluded.…”

“…The symptoms of anxiety and depression were measured with the Hospital Anxiety and Depression Scale (HADS), which was reported in our previous study. 29 …”

“…All the subjects came from the Emotion and Health among Occupational Population (EHOP) study which was a registry study to explore the associations between emotional factors and physical health among Chinese occupational population 29 . There were 300 workers anticipated this study when they underwent physical checkups at the Peking University Third Hospital in August 2016.…”

“…The Cronbach's alpha coefficient of extrinsic effort, reward, and overcommitment was 0.81, 0.87 and 0.79, respectively. The symptoms of anxiety and depression were measured with the Hospital Anxiety and Depression Scale (HADS), which was reported in our previous study 29 …”

Extended-gate-type Organic Field-effect Transistors for the Detection of Potential Psychological Stress Markers

“…(43) Thus, CgA is a sensitive biomarker for psychophysical stress, (44) such as exposure to situations inducing anxiety and depressive moods. (45) In addition, serum CgA is an early biomarker for the monitoring of endocrine tumors, (46) hypertensive heart failure, (38) and neurodegenerative/neuropsychiatric diseases (e.g., amyotrophic lateral sclerosis (ALS), (10) Alzheimer's disease, (38) and Parkinson's disease. (47) In other words, CgA is important for diagnosing chronic psychological stress and malfunction of the sympathetic nervous system.…”