The Association of Public Health Observatories (APHO) Diabetes Prevalence Model: estimates of total diabetes prevalence for England, 2010–2030

Holman, Naomi; Forouhi, Nita G.; Goyder, Elizabeth

doi:10.1111/j.1464-5491.2010.03216.x

Cited by 116 publications

(97 citation statements)

References 22 publications

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“…One possible explanation is that since the publication of the paper by Harris et al in 1992 [9] there has been an increased awareness in clinical practice of the high prevalence of undiagnosed diabetes, which has led to greater testing and earlier detection. The observation in the UK of a changing ratio of diagnosed to undiagnosed type 2 diabetes supports this view, as in the early 1990s the ratio was 1:1 [12] but is now reported to be closer to 2:1 [23]. However, the estimate by Harris et al of 9-12 years related to the true point of onset of diabetes, which is not the same as the point at which it is detected by screening, especially if screening is infrequent.…”

Section: Discussionsupporting

confidence: 51%

How much does screening bring forward the diagnosis of type 2 diabetes and reduce complications? Twelve year follow-up of the Ely cohort

et al. 2012

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Aims There are continuing uncertainties about how much screening for type 2 diabetes brings forward the clinical diagnosis and the impact that earlier diagnosis has on health outcomes. We compared the duration of diabetes and health outcomes in a population invited for diabetes screening at 5-yearly intervals from 1990 (screened population) with those in a similar population not invited for screening (unscreened population). Methods This was a parallel-group, cohort study of people aged 40-65 years, free of known diabetes, identified from the population register of a general practice in Ely, Cambridgeshire, UK (n04,936). In 1990-1992, one-third (n01,705), selected randomly, received an invitation for screening for diabetes and cardiovascular risk factors at 5-yearly intervals (screened population). From the remainder of the sampling frame, 1,705 randomly selected individuals were invited to diabetes screening 10 years later (unscreened population). Patients with diabetes from both populations were invited for a health assessment, including biochemical, anthropometric and questionnaire measures, and testing for the presence of diabetic complications Results Of the 199 eligible individuals with diabetes diagnosed during follow-up, 152 (76%) attended for health assessment. The median duration of clinically recognised diabetes was significantly longer in cases arising in the screened (5.0 years) compared with the unscreened population (1.7 years; p00.006). Clinical measures, prescribed medication and functional status were similar between screened and unscreened populations. Conclusions Diabetes screening resulted in cases being identified on average 3.3 years earlier, a difference significantly shorter than previous estimates. Earlier diagnosis did not appear to impact on health outcomes. Further evidence is needed to justify the introduction of population-based screening.

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Section: Discussionsupporting

confidence: 51%

How much does screening bring forward the diagnosis of type 2 diabetes and reduce complications? Twelve year follow-up of the Ely cohort

et al. 2012

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“…Around 388 000 South Asian people live with diagnosed or undiagnosed type 2 diabetes in the UK. 6,7 'If we want an equitable health service for people with diabetes we need to target the most disadvantaged groups, such as the white poor and people from ethnic minorities living in inner cities,' commented Professor Hanif. 'PHBs are most likely to benefit the middleclasses in green suburbia.…”

Section: Will Phbs Reach Those In Most Need?mentioning

confidence: 98%

Personal health budgets: a divisive development?

Greener¹

2014

Practical Diabetes

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“…90% stellt der Typ 2 Diabetes die größte Untergruppe dar. Innerhalb der letzten Jahrzehnte war seine Prävalenz steigend und es wird davon ausgegangen dass sich dieser Trend in Zukunft fortsetzen wird [28,72]. Wie die CODE-2 Studie gezeigt hat, entstehen auf…”

Section: Bedeutung Und Mögliche Ursachen Der Insulinresistenzunclassified

Untersuchungen zur möglichen Rolle des Prohibitin 1 bei der Entstehung der Insulinresistenz

Jaghutriz¹,

Giebelstein²,

Klein³

2014

Diabetologie und Stoffwechsel

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The Association of Public Health Observatories (APHO) Diabetes Prevalence Model: estimates of total diabetes prevalence for England, 2010–2030

Cited by 116 publications

References 22 publications

How much does screening bring forward the diagnosis of type 2 diabetes and reduce complications? Twelve year follow-up of the Ely cohort

How much does screening bring forward the diagnosis of type 2 diabetes and reduce complications? Twelve year follow-up of the Ely cohort

Personal health budgets: a divisive development?

Untersuchungen zur möglichen Rolle des Prohibitin 1 bei der Entstehung der Insulinresistenz

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