The Association of Pregnancy-Induced Hypertension and Uterine Malformations

Abstract

To evaluate the incidence of pregnancy-induced hypertension (PIH) in women with congenital uterine malformations, we examined the pregnancy complications of 67 women with uterine anomalies demonstrated by hysterosalpingography (HSG). The study group was compared with a control group of 130 women with normal-shaped uterus proven by HSG – matched for age, parity and presenting complaint. A significantly increased (p < 0.04) rate of PIH was found for women with uterine malformation as well as a 2-fold higher frequency of preeclampsia. The etiology for this association is unknown, however; it is suggested that uterine malformation is a predisposing condition to PIH.

Bicornuate [Bicornis, Unicollis] Uterus, a Congenital Malformation Associated With Pathological Le Sions: A Clinicopathological Stu Dy of 4 Rare Cases

“…12,13 Despite this documented reproductive success in women with malformed uteri, there is still considerable debate about infertility, early pregnancy loss, premature labor and intrauterine growth retardation 14,15 and pre-eclampsia. 16 This association of uterine malformations with endometriosis is well known entity, but is in fact only true for those cases in which there is obstruction to the menstrual out flow 17,18 . This is one of the strongest arguments for the menstrual reflex hypothesis of the pathogenesis of endometriosis.…”

Congenital Uterine Anomaly: An Incidental Diagnosis-Report of Two Interesting Cases

“…He reported a significantly increased (p less than 0.04) rate of PIH in woman with uterine malformation as well as a 2-fold higher frequency of preeclampsia. In our first case patient also had PIH [6]. Ludmir et al conducted studies for 8 years managing 42 women swith 101 pregnancies with previously diagnosed but uncorrected uterine malformations referred to the institution for high-risk obstetric care.…”

Impact of congenital uterine anomalies on obstetric and perinatal outcomes: systematic review and meta-analysis

“…Scores granted by Newcastle-Ottawa Score and quality assessment using AHRQ standards are presented in Appendix 2 . Reasons for exclusion of non-included studies ( Acién, 1993 ; Acién et al, 2014 ; Airoldi et al, 2005 ; Akar et al, 2005 ; Alonso Pacheco et al, 2019 ; Ben-Rafael et al, 1990 ; Colacurci et al, 1996 ; Chen et al, 2013 ; Elsokkary et al, 2018 ; Fedele and Bianchi, 1995 ; Fox et al, 2019 ; Fox et al, 2014 ; Gabbai et al, 2018 ; Ghi et al, 2012 ; Grimbizis et al, 2001 ; Hynes et al, 2021 ; Jaslow and Kutteh, 2013 ; Lavergne et al, 1996 ; Liang and Hu, 2010 ; Ludwin, 2018 ; Maneschi et al, 1995 ; Neal et al, 2019 ; Portuondo et al, 1986 ; Raga et al, 1997 ; Ravasia et al, 1999 ; Ridout et al, 2019 ; Rogers and Needham, 1985 ; Salim et al, 2003 ; Sendag et al, 2010 ; Shuiqing et al, 2002 ; Sorensen and Trauelsen, 1987 ; Sugiura-Ogasawara et al, 2015 ; Tofoski and Antovska, 2014 ; Tomazevic et al, 2007 ; Tonguc et al, 2011 ; Woelfer et al, 2001 ; Zhang et al, 2010 ; Zupi et al, 1996 ) are described in Table SII .…”