The association of pre-operative biomarkers of endothelial dysfunction with the risk of post- operative neurocognitive disorders: Results from BioCog study
Sara Moazzen,
Jürgen Janke,
Arjen Slooter
et al.
Abstract:Introduction: Endothelial dysfunction (ED) promotes atherosclerosis development, and studies suggest an association with age-related neurocognitive disorders. Nonetheless, it is unclear whether ED is associated with the risk of neurocognitive disorders.
Method: We included 788 participants aged ≥65 years in the BioCog study. Blood was collected before surgery for measurement of 5 biomarkers of ED including asymmetric and symmetric dimethylarginine (ADMA; SDMA), intercellular and vascular adhesion molecule (IC… Show more
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