The Association of Periodontal Treatment and Decreased Pneumonia: A Nationwide Population-Based Cohort Study

Yang, Li‐Chiu; Suen, Yih-Jane; Wang, Yu‐Hsun; Lin, Taichen; Yu, Hui-Chieh; Chang, Yu‐Chao

doi:10.3390/ijerph17010356

Cited by 34 publications

(31 citation statements)

References 26 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Some epidemiologic studies found no clear relationship between periodontal hygiene and acute respiratory disease 31,32 . However, some studies have reported the association between periodontal disease and pneumonia [33][34][35] , and Yang et al reported that patients with periodontal treatment exhibited a decreased risk of pneumonia 36 . In this study, NHIS-HealS data did not include the severity and treatment of periodontal disease; therefore, the two factors could potentially be found to be unrelated.…”

Section: Discussionmentioning

confidence: 99%

Association between oral health and incidence of pneumonia: a population-based cohort study from Korea

Son

Lee

et al. 2020

Sci Rep

View full text Add to dashboard Cite

pneumonia is related to oral health of the elderly and intensive care unit patients. However, studies on the relationship between overall oral health and pneumonia in the general population have been limited. the purpose of this study was to investigate the association between oral health and pneumonia using a nationwide population-based Korean cohort database. Data from 122,251 participants who underwent health screening and oral examinations in 2004 or 2005 were analyzed. Cox proportional hazard regression analysis was performed to evaluate the association between oral health and pneumonia. The risk of pneumonia increased significantly in groups with a higher number of dental caries and missing teeth, with respective adjusted hazard ratios (HRs) and 95% confidence interval (CI) of 1.265 (1.086-1.473; p = 0.0025) and 1.218 (1.113-1.332; p < 0.0001), and decreased significantly in frequent tooth brushing and regular professional dental cleaning groups, with respective adjusted HRs and 95% CI of 0.853 (0.786-0.926; p = 0.0001) and 0.920 (0.855-0.990; p = 0.0255). In addition, regardless of age and comorbidities, oral health status and oral hygiene behaviors were associated with pneumonia. the results indicate that improved oral health may reduce the risk of pneumonia in the general population. Pneumonia is a debilitating disease that can result in death in elderly individuals 1 and has been reported to be related to oral health 2. The oral cavity is a complex environment for multiple microorganisms and cytokines 3. In particular, aspiration of microorganisms and biological mediators such as cytokines and hydrolytic enzymes from the oral cavity can provoke inflammation and cause infections 4,5. The association between pneumonia and oral health has been examined in nursing homes, and the incidence of pneumonia has been reported to be lower in elderly populations receiving oral care 6. Besides, several studies have suggested that hospitalized intensive care unit (ICU) patients appear to benefit from daily oral cleansing 7,8. Oral hygiene can be improved through individual-based interventions 9. Daily personal oral hygiene behaviors such as tooth brushing are fundamental in the prevention of periodontal disease and bacterial plaque, which can respectively lead to tooth loss and dental caries 10,11. In addition, professional dental cleaning has been proven to reduce periodontal disease, dental caries, and tooth loss 12. Dentists recommend tooth brushing at least twice daily as well as regular dental visits for professional dental cleaning 13. While the link between pneumonia and oral health has been gaining increased attention, studies evaluating the relationship between overall oral health and pneumonia in the general population have been limited. The purpose of this study was to investigate the association between oral health and pneumonia using a nationwide population-based Korean cohort from the National Health Insurance Service-Health Screening (NHIS-HealS) database. Methods Data source. This study used the NHIS-H...

show abstract

Section: Discussionmentioning

confidence: 99%

Association between oral health and incidence of pneumonia: a population-based cohort study from Korea

Son

Lee

et al. 2020

Sci Rep

View full text Add to dashboard Cite

show abstract

“…The LHID2010 incorporates 1 million patients’ insurance claims data from the total of 23 million Taiwan NHI beneficiaries in the year 2010. There are no demographic characteristic differences between the LHID2010 and the original NHIRD [ 16 , 17 ]. The LHID2010 contains the most updated claims data of sampled individuals from 1997.…”

Section: Methodsmentioning

confidence: 99%

Increased Risk of Migraine in Patients with Chronic Periodontitis: A Population-Based Cohort Study

Huang

Yang

Wang

et al. 2021

IJERPH

Self Cite

View full text Add to dashboard Cite

Migraine is considered to be a neurovascular disease that manifests as a throbbing headache, possibly caused by the activation of the trigeminovascular system. Several studies have supported the role of inflammation in the pathogenesis of migraine. Chronic periodontitis (CP) is an infectious inflammatory disease triggered by bacterial products evoking an immune response which could result in the destruction of the periodontium. However, little is known about the longitudinal association between CP and migraine. In this study, we designed a nationwide population-based cohort study to investigate the risk of migraine and CP exposure in Taiwan. In total, 68,282 patients with CP were identified from the National Health Insurance Research Database (NHIRD), and 68,282 comparisons were randomly captured and matched by age, sex, monthly income, urbanization and comorbidities. The association between CP exposure and migraine risk was evaluated by Cox proportional hazards regression models. In this study, 785 migraine patients were identified in the CP cohort, and 641 migraine cases were found in the non-CP cohort. The incidence rate of migraine was significantly higher in the CP cohort than the non-CP cohort (adjusted HR: 1.21, 95% CI: 1.09–1.34, p < 0.001) during the 13-year follow-up period. Females had a 2.69-fold higher risk for migraine than males (95% CI: 2.38–3.04, p < 0.001). In summary, CP is associated with an increased risk of subsequent migraine in Taiwan.

show abstract

“…Patients with diabetes had a 78% increased risk of developing pneumonia compared to the control group. 12 These findings indicate that the multimorbid patient with diabetes and periodontitis as a comorbidity has a frighteningly high risk of pneumonia even without SARS-CoV-2 infection.…”

mentioning

confidence: 80%

Why Do People With Diabetes Have a High Risk for Severe COVID-19 Disease?—A Dental Hypothesis and Possible Prevention Strategy

Pfützner¹,

Lazzara

Jantz

2020

J Diabetes Sci Technol

View full text Add to dashboard Cite

The Association of Periodontal Treatment and Decreased Pneumonia: A Nationwide Population-Based Cohort Study

Abstract: Pneumonia is a common respiratory infectious disease that involves the inflammation of the pulmonary parenchyma. Periodontal disease is widespread and correlated with pneumonia.

Cited by 34 publications

References 26 publications

Association between oral health and incidence of pneumonia: a population-based cohort study from Korea

Association between oral health and incidence of pneumonia: a population-based cohort study from Korea

Increased Risk of Migraine in Patients with Chronic Periodontitis: A Population-Based Cohort Study

Why Do People With Diabetes Have a High Risk for Severe COVID-19 Disease?—A Dental Hypothesis and Possible Prevention Strategy

Contact Info

Product

Resources

About