The association of pelvic organ prolapse severity and improvement in overactive bladder symptoms after surgery for pelvic organ prolapse

Kim, Mi Sun; Lee, Gee Hoon; Na, Eun Duc; Jang, Ji Hyon; Kim, Hyeon Chul

doi:10.5468/ogs.2016.59.3.214

Cited by 26 publications

(22 citation statements)

References 18 publications

(30 reference statements)

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“…A possible explanation would be that older women have more severe damage to nerves and detrusor muscles in the bladder than younger women. However, as with our results, many authors concluded that age was not a predictive factor for persistence of preoperative OAB symptoms after POP surgery . The present study showed that the severity of POP was not a predictive factor for persistence of preoperative OAB symptoms after POP surgery.…”

Section: Discussionsupporting

confidence: 78%

“…To date, it is well accepted that parity and BMI are not predictive factors for postoperative OAB symptoms after POP surgery . In contrast, it remains controversial whether age and the severity of POP are predictors of postoperative OAB symptoms after POP surgery.…”

Section: Discussionmentioning

confidence: 99%

“…The present study showed that the severity of POP was not a predictive factor for persistence of preoperative OAB symptoms after POP surgery. Many studies have also demonstrated that POP stage is not predictive for postoperative OAB symptoms, while Miranne et al demonstrated that women with more severe POP (stage 3 and 4) were at a higher risk of persistent frequency or urge incontinence …”

Section: Discussionmentioning

confidence: 99%

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Predictive factors for persistence of preoperative overactive bladder symptoms after transvaginal mesh surgery in women with pelvic organ prolapse

Otsuka

Watanabe

Matsushita

et al. 2019

LUTS

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Background: We aimed to evaluate the effect of transvaginal mesh surgery on overactive bladder symptoms in women with pelvic organ prolapse and to identify predictive factors for persistence of a preoperative overactive bladder after surgery. Materials and Methods:We retrospectively evaluated 102 patients who underwent transvaginal mesh surgery. All patients had stage 2 or greater pelvic organ prolapse accompanied by cystocele. The Overactive Bladder Symptom Score, International Prostate Symptom Score, uroflowmetry, and postvoid residual urine volume were evaluated preoperatively and 6 months postoperatively. To identify predictive factors for the persistence of a preoperative overactive bladder after surgery, preoperative parameters were statistically compared between patients with and without the persistence of preoperative overactive bladder symptoms. Receiver operator characteristic curves were generated, and the area under the curve was calculated.Results: Preoperatively, 54 women (53%) had an overactive bladder. After surgery, the symptoms disappeared in 34 (63%) and persisted in 20 (37%) women. There were no significant differences in preoperative parameters including age, body mass index, parity, or severity of pelvic organ prolapse between patients with and without persistent preoperative overactive bladder. Preoperative Overactive Bladder Symptom Score and International Prostate Symptom Score were significantly higher in patients with persistent preoperative overactive bladder symptoms. The International Prostate Symptom Score storage subscore had the highest area under the curve, with a cutoff value of 9.5. Conclusion: Transvaginal mesh surgery eliminates overactive bladder symptoms inabout two-thirds of pelvic organ prolapse patients. The preoperative International Prostate Symptom Score storage subscore was the most useful predictive factor for the persistence of preoperative overactive bladder symptoms after surgery. K E Y W O R D S female, International Prostate Symptom Score, overactive bladder, pelvic organ prolapse, transvaginal mesh surgery

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Section: Discussionsupporting

confidence: 78%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Predictive factors for persistence of preoperative overactive bladder symptoms after transvaginal mesh surgery in women with pelvic organ prolapse

Otsuka

Watanabe

Matsushita

et al. 2019

LUTS

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“…Surgical repair of pelvic organ prolapse has been shown to improve UUI in the majority of patients. 3 Levator ani pelvic floor muscle injury, sphincteric injury, and/or pudendal nerve injury may be also present in a subset of patients who have concomitant UI, pelvic organ prolapse, and fecal incontinence. 2,17,18 Thus, our finding that increasing UI severity was associated with more distress from prolapse symptoms was not surprising.…”

Section: Discussionmentioning

confidence: 99%

Bowel function, sexual function, and symptoms of pelvic organ prolapse in women with and without urinary incontinence

Cameron

Smith

Lai

et al. 2018

Neurourology and Urodynamics

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Aims Bowel symptoms, pelvic organ prolapse, and sexual dysfunction are common, but their frequency among women with lower urinary tract symptoms (LUTS) has not been well described. Our aims were to describe pelvic floor symptoms among women with and without urinary incontinence (UI) and among subtypes of UI. Methods Women with LUTS seeking care at six U.S. tertiary care centers enrolled in prospective cohort study were studied. At baseline, participants completed the Pelvic Floor Distress Inventory (PFDI-20), Pelvic Organ Prolapse/Incontinence Sexual Questionnaire (PISQ-IR), and PROMIS GI Diarrhea, Constipation, and Fecal Incontinence Scales. Results Mean age among the 510 women was 56.4 ± 14.4 years. Women who reported UI (n=420) had more diarrhea and constipation symptoms (mean scores 49.5 vs 46.2 [p=0.01] and 51.9 vs 48.4 [p<0.01], respectively) at baseline. Among sexually active women, mean PISQ-IR subscale scores were lower among those with UI (condition specific: 89.8 vs 96.7, p<0.01; condition impact: 79.8 vs 92.5, p<0.01). Women with mixed urinary incontinence (MUI) (n=240) reported more prolapse symptoms, fecal incontinence, and worse sexual function compared to those with stress urinary incontinence (SUI) and urgency urinary incontinence (UUI). Conclusions Women presenting with LUTS with UI reported significantly worse constipation, diarrhea, fecal incontinence, and sexual function compared to women without UI. In women with UI, sexual function and pelvic organ prolapse (POP) symptoms were worse in those with MUI compared to SUI and UUI.

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“…In contrast, Miranne et al [21] found that more women with stage 3-4 POP (35%) had urodynamic DO than women with lower grade 1 or 2 POP (17%). Regardless of the stage of POP after repair, OAB symptoms of urgency and frequency improve similarly in women with stage 1 or 2 POP compared to women with stage 3 or 4 [22].…”

Section: Does Worse Pop Lead To Worse Oab?mentioning

confidence: 87%

Systematic review of lower urinary tract symptoms occurring with pelvic organ prolapse

Cameron

2019

Arab Journal of Urology

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Objective: To review lower urinary tract symptoms (LUTS), which include a large variety of bladder complaints, in women with simultaneous pelvic organ prolapse (POP). Methods: This article is a systematic review of the current literature on LUTS occurring simultaneously with POP following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) methodology. Results: The prevalence of both conditions is high, but they occur more frequently together than can be explained by chance. It appears that POP is in some women causative of overactive bladder (OAB) symptoms, as in many women correction of the POP resolves the bladder symptoms and small studies of women with detrusor underactivity also demonstrate resolution of symptoms. The most plausible explanation for the relationship is that POP causes bladder outlet obstruction, which results in excess bladder irritability or poor contractility. However, not all women have resolution of their OAB symptoms and some women develop them de novo after POP repair, so this explanation requires more in depth study. Conclusions: Women with both LUTS and symptomatic POP should probably have their POP targeted, as its reduction either via surgery or pessary can correct the LUTS. However, no studies have addressed asymptomatic POP, so it is unclear if treating POP in these instances is of benefit.

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The association of pelvic organ prolapse severity and improvement in overactive bladder symptoms after surgery for pelvic organ prolapse

Cited by 26 publications

References 18 publications

Predictive factors for persistence of preoperative overactive bladder symptoms after transvaginal mesh surgery in women with pelvic organ prolapse

Predictive factors for persistence of preoperative overactive bladder symptoms after transvaginal mesh surgery in women with pelvic organ prolapse

Bowel function, sexual function, and symptoms of pelvic organ prolapse in women with and without urinary incontinence

Systematic review of lower urinary tract symptoms occurring with pelvic organ prolapse

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