The association of insight with psychotic symptoms, depression, and cognition in early psychosis: A 3-year follow-up

Saeedi, Huma; Addington, Jean; Addington, Donald

doi:10.1016/j.schres.2006.09.018

Cited by 89 publications

(83 citation statements)

References 30 publications

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“…In a first-episode follow-up study [28] involving 145 participants (of 248 eligible) with nonaffective psychosis, better insight correlated moderately and increasingly with better social function measured on the observer-rated Quality of Life Scale. Cross-sectional associations of good insight in consecutive first admissions in West London included better performance of everyday activity [14].…”

Section: Quality Of Life and Social Functionmentioning

confidence: 99%

Insight into illness: Impact on diagnosis and outcome of nonaffective psychosis

Drake

2008

Curr Psychiatry Rep

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Insight is a reliably measured construct that is stable across cultures, with several aspects assessed frequently. Insight impairment in schizophrenia appears to be more stable than in mania and tends to be worse at all stages than other psychoses or "at-risk states." Good insight may lead to temporary low mood and poor self-image, but these processes are complex and perhaps not the same at different stages of illness. Depression and hopelessness mediate insight's relationship with suicidality. Insight predicts low self-rating of quality of life but better observer rating and social function. It did not predict violence in one large study but did in shorter-term studies of forensic or first-admission populations. First-episode studies find consistent links with relapse and readmission but weak evidence of insight predicting symptoms or function at follow-up. Atypical antipsychotics were not specifically beneficial in one large trial, but cognitive-behavioral therapy was in another.

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Section: Quality Of Life and Social Functionmentioning

confidence: 99%

Insight into illness: Impact on diagnosis and outcome of nonaffective psychosis

Drake

2008

Curr Psychiatry Rep

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“…In reality, the correlations between insight and symptoms are rather modest (Mintz et al, 2003). Another reason for the lack of interventions aiming to improve insight might be the idea that improved insight leads to an increase in depressive symptoms (Saeedi et al, 2007). However, this was not confirmed in a recent meta-analysis, which showed that improving insight with psychosocial interventions may even be associated with a better mood (Pijnenborg et al, 2012).…”

Section: Introductionmentioning

confidence: 99%

Differential effects of antipsychotic drugs on insight in first episode schizophrenia: Data from the European First-Episode Schizophrenia Trial (EUFEST)

Pijnenborg¹,

Timmerman²,

Derks³

et al. 2015

European Neuropsychopharmacology

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“…5 As such, awareness of a mental disorder also includes awareness of the need to take medication and of the social consequences of the mental disorder. 6 Impaired insight has been associated with disease severity, 7 cognitive deficits 8,9 and with social and vocational functioning impairments. 8,9 On the other hand, preserved insight has been suggested to be predictive of treatment outcome in patients with schizophrenia.…”

Section: Introductionmentioning

confidence: 99%

“…6 Impaired insight has been associated with disease severity, 7 cognitive deficits 8,9 and with social and vocational functioning impairments. 8,9 On the other hand, preserved insight has been suggested to be predictive of treatment outcome in patients with schizophrenia. 3,10,11 Preserved insight is linked in particular with improved adherence to treatment 12 and reduced risk of relapse and readmission to hospital.…”

Section: Introductionmentioning

confidence: 99%