2021
DOI: 10.3390/ijerph18137045
|View full text |Cite
|
Sign up to set email alerts
|

The Association of Familial Hypertension and Risk of Gestational Hypertension and Preeclampsia

Abstract: It has not been established how history of hypertension in the father or mother of pregnant women, combined with obesity or smoking, affects the risk of main forms of pregnancy-induced hypertension. A cohort of 912 pregnant women, recruited in the first trimester, was assessed; 113 (12.4%) women developed gestational hypertension (GH), 24 (2.6%) developed preeclampsia (PE) and 775 women remained normotensive (a control group). Multiple logistic regression was used to calculate adjusted odds ratios (AOR) (and 9… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1
1
1

Citation Types

0
5
0
1

Year Published

2022
2022
2023
2023

Publication Types

Select...
6

Relationship

1
5

Authors

Journals

citations
Cited by 8 publications
(6 citation statements)
references
References 34 publications
0
5
0
1
Order By: Relevance
“…As per the gestosis score, three categories of scoring factors exist. Studies have individually found risk association with these factors [ 23 40 ], thereby justifying the inclusion of these factors in gestosis score.…”
Section: Discussionmentioning
confidence: 99%
“…As per the gestosis score, three categories of scoring factors exist. Studies have individually found risk association with these factors [ 23 40 ], thereby justifying the inclusion of these factors in gestosis score.…”
Section: Discussionmentioning
confidence: 99%
“…Paternal and maternal family history of hypertension is a known risk factor in preeclampsia [90,91]. Consistent with the natriuretic peptide function in regulating blood volume and pressure, variants at the MTHFR-CLCN6 locus on 1p36, where NPPA and NPPB genes are present, have been associated with blood pressure levels in human populations [54,92].…”
Section: Genetic Loci Associated With Gestational Hypertension and Pr...mentioning
confidence: 92%
“…We selected verified or possible risk factors for HDP as covariates, including age during antenatal care at 10-13 weeks of gestation, 24 pre-pregnancy body mass index (BMI), 24 chronic hypertension (CH), systemic lupus erythematosus (SLE), 24 diabetes mellitus (DM), 24 family (mother and sisters) history of HDP, 24 conception by in vitro fertilization (IVF), 24 parity (nulliparous, parous with previous HDP, or parous without previous HDP), 24 educational attainment, 25 smoking status during early pregnancy, 26,27 alcohol consumption during early pregnancy, 28 and family (father, mother, brothers, and sisters) history of CH. 29 Basic maternal characteristics were obtained from self-reports by the pregnant women, and pre-pregnancy weight and height were retrieved from the medical records to calculate the pre-pregnancy BMI. 24 We previously developed a prediction model for PE and superimposed PE (SP) using competing risk model, [30][31][32] consisting of basic characteristics routinely collected during antenatal care in Japan.…”
Section: Exposures and Other Covariatesmentioning
confidence: 99%